In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

The isatin framework is a useful template for the development of novel anticancer agents.
This is exemplified by the fact that several isatin‐based anticancer agents, such as …

Indisulam (IDM) is a sulfanilamide anticancer agent and has been identified as a molecular
glue recently. It shows potential for novel therapies development and brings more hope for …

Increasing evidence supports that activation of store‐operated Ca2+ entry (SOCE) is
implicated in the chemoresistance of cancer cells subjected to chemotherapy. However, the …

The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

One of the most important therapies of malignant neoplasms, which are the second cause of
death worldwide, is focused on the inhibition of pathological angiogenesis within the tumor …

In this research, twenty-four hydrazide–hydrazones of 2, 4-dihydroxybenzoic acid were
designed, synthesized, and subjected to in vitro and in vivo bioactivity studies. The chemical …

In this study, a series of hydrazide-hydrazone derivatives (3a-3u) were synthesized and
evaluated for their anticancer activities against prostate cancer cell line (PC-3), breast …

Esterification of (4-hydroxyphenyl) diphenylphosphine, coordinated to the [Ru (η6-p-
cymene) Cl2] fragment, allows a series of bioactive carboxylic acids to be introduced directly …

Abstract 6PPD and its oxidation product, 6PPD-quinone have garnered widespread
attention due to their adverse effects on aquatic ecosystems and human health, and are …