The role of sex in the genomics of human complex traits
Nearly all human complex traits and disease phenotypes exhibit some degree of sex
differences, including differences in prevalence, age of onset, severity or disease …
differences, including differences in prevalence, age of onset, severity or disease …
Conservation, acquisition, and functional impact of sex-biased gene expression in mammals
INTRODUCTION Sex differences are widespread in humans and other mammals. For
example, the distribution of height or body size is shifted upwards in males relative to …
example, the distribution of height or body size is shifted upwards in males relative to …
Tissue-specific sex differences in human gene expression
Despite extensive sex differences in human complex traits and disease, the male and
female genomes differ only in the sex chromosomes. This implies that most sex …
female genomes differ only in the sex chromosomes. This implies that most sex …
Paternal impact on the developmental programming of sexual dimorphism
SM Aljabali, S Pai, R Teperino - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Sexual dimorphism involves distinct anatomical, physiological, behavioral, and
developmental differences between males and females of the same species, influenced by …
developmental differences between males and females of the same species, influenced by …
RNA-seq analysis for detecting quantitative trait-associated genes
Many recent RNA-seq studies were focused mainly on detecting the differentially expressed
genes (DEGs) between two or more conditions. In contrast, only a few attempts have been …
genes (DEGs) between two or more conditions. In contrast, only a few attempts have been …
Sexual dimorphism and aging in the human hyppocampus: identification, validation, and impact of differentially expressed genes by factorial microarray and network …
DV Guebel, NV Torres - Frontiers in aging neuroscience, 2016 - frontiersin.org
Motivation: In the brain of elderly-healthy individuals, the effects of sexual dimorphism and
those due to normal aging appear overlapped. Discrimination of these two dimensions …
those due to normal aging appear overlapped. Discrimination of these two dimensions …
Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs
M Piles, C Fernandez-Lozano… - Genetics Selection …, 2019 - Springer
Background To date, the molecular mechanisms that underlie residual feed intake (RFI) in
pigs are unknown. Results from different genome-wide association studies and gene …
pigs are unknown. Results from different genome-wide association studies and gene …
Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils
M Sabino, VAO Carmelo, G Mazzoni, K Cappelli… - BMC genomics, 2018 - Springer
Background Essential oil (EO) dietary supplementation is a new strategy to improve animal
health. EO compounds have antiparasitic, antimicrobial, antiviral, antimycotic, antioxidant …
health. EO compounds have antiparasitic, antimicrobial, antiviral, antimycotic, antioxidant …
Whole genome analyses revealed genomic difference between European taurine and East Asian taurine
Abstract European taurine and East Asian taurine are two main clades in Bos taurus, but
their genomic differences are not clearly elucidated. Here, we sequenced 16 Mongolian …
their genomic differences are not clearly elucidated. Here, we sequenced 16 Mongolian …
Developmental Programming: Sex-specific Effects of Prenatal Exposure to a Real-Life Mixture of Environmental Chemicals on Liver Function and Transcriptome in …
Humans are chronically exposed to a mixture of environmental chemicals (ECs), many with
metabolic and endocrine disrupting potential, contributing to non-communicable disease …
metabolic and endocrine disrupting potential, contributing to non-communicable disease …