Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ involvement, including the skin, joints, kidneys, lungs, central nervous system and the …

Inhaled toxicants drive the onset of and exacerbate preexisting chronic pulmonary diseases,
however, the biological mechanisms by which this occurs are largely unknown. Exposure to …

Introduction Phagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident
alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived …

Epidemiological studies have confidently linked occupational crystalline silica exposure to
autoimmunity, but pathogenic mechanisms and role of genetic predisposition remain poorly …

Chemical pollutant exposure is a risk factor contributing to the growing epidemic of non-
alcoholic fatty liver disease (NAFLD) affecting human populations that consume a western …

Objective To examine associations between dietary intake of omega‐3 (n‐3; generally
antiinflammatory) and omega‐6 (n‐6; generally proinflammatory) fatty acids and patient …

Ectopic lymphoid structures (ELS) consist of B-cell and T-cell aggregates that are initiated de
novo in inflamed tissues outside of secondary lymphoid organs. When organized within …

Introduction Lipopolysaccharide (LPS)-accelerated autoimmune glomerulonephritis (GN) in
NZBWF1 mice is a preclinical model potentially applicable for investigating lipidome …

Occupational exposure to crystalline silica (cSiO2) is etiologically associated with systemic
lupus erythematosus (lupus) and other autoimmune diseases. cSiO2's autoimmune effects …

Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and
other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 …