The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

A commercial quadrupole/time-of-flight tandem mass spectrometer has been modified and
evaluated for its performance in conducting ion/ion reaction studies involving high mass (> …

Electron capture dissociation (ECD) is now a well-established method for sequencing
peptides and performing top-down analysis on proteins of less than 30 kDa, and there is …

The combination of native electrospray ionization with top-down fragmentation in mass
spectrometry (MS) allows simultaneous determination of the stoichiometry of noncovalent …

Digital mass filters are advantageous for the analysis of large molecules due to the ability to
perform ion isolation of high-m/z ions without the generation of very high radio frequency …

The combination of a linear quadrupole ion-filter and linear Paul trap operated with a
rectangular guiding field for the filtering and accumulation of ions within the Mass …

We present the implementation of tandem mass-selective cryogenic ion traps, designed to
enhance the range of ion processing capabilities that can be performed prior to …

The performance of a segmented quadrupole mass filter operated with rectangular
waveforms and capacitively coupled rectangular waveforms applied to the prefilters was …

Abstract The Fourier Transform Ion Cyclotron Resonance mass spectrometer (FT-ICR MS) is
an efficient and widely used analytical instrument for characterizing complex organic …

Recent improvements to the comparison-based method of digital waveform generation
increased the reproducibility of the waveforms so that the higher-order Mathieu stability …