Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges

D Tsikas - Analytical biochemistry, 2017 - Elsevier
Abstract Malondialdehyde (MDA), 4-hydroxy-nonenal (HNE) and the F 2-isoprostane 15 (S)-
8-iso-prostaglandin F 2α (15 (S)-8-iso-PGF 2α) are the best investigated products of lipid …

[HTML][HTML] ROS in platelet biology: functional aspects and methodological insights

E Masselli, G Pozzi, M Vaccarezza… - International journal of …, 2020 - mdpi.com
Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet
functions. Platelet activation determines a drastic change in redox balance and in platelet …

Markers of oxidative stress during diabetes mellitus

BK Tiwari, KB Pandey, AB Abidi… - Journal of biomarkers, 2013 - Wiley Online Library
The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of
hyperglycemia due to defects in insulin secretion/action leads to a variety of complications …

Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

WI Sivitz, MA Yorek - Antioxidants & redox signaling, 2010 - liebertpub.com
Given their essential function in aerobic metabolism, mitochondria are intuitively of interest
in regard to the pathophysiology of diabetes. Qualitative, quantitative, and functional …

Antioxidants and prevention of chronic disease

JK Willcox, SL Ash, GL Catignani - Critical reviews in food science …, 2004 - Taylor & Francis
The generation of reactive oxygen species (ROS) and other free radicals (R•) during
metabolism is a necessary and normal process that ideally is compensated for by an …

Pathological aspects of lipid peroxidation

A Negre-Salvayre, N Auge, V Ayala, H Basaga… - Free radical …, 2010 - Taylor & Francis
Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

Isoprostane generation and function

GL Milne, H Yin, KD Hardy, SS Davies… - Chemical …, 2011 - ACS Publications
Free radicals derived primarily from molecular oxygen have been implicated in a variety of
human disorders including atherosclerosis, cancer, neurodegenerative diseases, and aging …

Factors associated with oxidative stress in human populations

G Block, M Dietrich, EP Norkus… - American journal of …, 2002 - academic.oup.com
Oxidation of biomolecules may play a role in susceptibility to a number of diseases.
However, there are few large-scale survey data describing oxidative damage that occurs in …

[HTML][HTML] Carotenoids from marine microalgae: A valuable natural source for the prevention of chronic diseases

MFJ Raposo, AMMB Morais, RMSC Morais - Marine drugs, 2015 - mdpi.com
Epidemiological studies have shown a relation between antioxidants and the prevention of
several chronic diseases. Microalgae are a potential novel source of bioactive molecules …

Lipid peroxidation in diabetes mellitus

G Davì, A Falco, C Patrono - Antioxidants & redox signaling, 2005 - liebertpub.com
There is considerable evidence that hyperglycemia represents the main cause of
complications of diabetes mellitus (DM), and oxidative stress resulting from increased …