Targeting different phenotypes of macrophages: A potential strategy for natural products to treat inflammatory bone and joint diseases
Y Gao, X Xu, X Zhang - Phytomedicine, 2023 - Elsevier
Background Macrophages, a key class of immune cells, have a dual role in inflammatory
responses, switching between anti-inflammatory M2 and pro-inflammatory M1 subtypes …
responses, switching between anti-inflammatory M2 and pro-inflammatory M1 subtypes …
[HTML][HTML] Global scientific trends update on macrophage polarization in rheumatoid arthritis: A bibliometric and visualized analysis from 2000 to 2022
J Yuan, T Feng, Y Guo, K Luo, Q Wu, S Yu, H Zhou - Heliyon, 2023 - cell.com
The goal of this work was to use bibliometric analysis to help guide future research on
macrophage polarization in RA. We looked for studies on macrophage polarization in RA …
macrophage polarization in RA. We looked for studies on macrophage polarization in RA …
Wogonin inhibits the migration and invasion of fibroblast-like synoviocytes by targeting PI3K/AKT/NF-κB pathway in rheumatoid arthritis
H Yang, C Liu, X Lin, X Li, S Zeng, Z Gong, Q Xu… - Archives of Biochemistry …, 2024 - Elsevier
Background Rheumatoid arthritis (RA) is currently an autoimmune inflammatory disease
with an unclear pathogenesis. Fibroblast-like synoviocytes (FLSs) have tumor-like …
with an unclear pathogenesis. Fibroblast-like synoviocytes (FLSs) have tumor-like …
Nesfatin-1 stimulates BMP5 expression and osteoclastogenesis in rheumatoid arthritis
Rheumatoid arthritis (RA) is a common autoimmune disease marked by immune cell
activation and chronic inflammation in the synovium accompanied by osteoclast activation …
activation and chronic inflammation in the synovium accompanied by osteoclast activation …
Macrophage polarization in rheumatoid arthritis: signaling pathways, metabolic reprogramming, and crosstalk with synovial fibroblasts
Y Zheng, K Wei, P Jiang, J Zhao, Y Shan, Y Shi… - Frontiers in …, 2024 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent
synovial inflammation and progressive joint destruction. Macrophages are key effector cells …
synovial inflammation and progressive joint destruction. Macrophages are key effector cells …
[HTML][HTML] Bone marrow adipocytes and lung cancer bone metastasis: unraveling the role of adipokines in the tumor microenvironment
J Li, J Wu, Y Xie, X Yu - Frontiers in Oncology, 2024 - frontiersin.org
Bone is a common site of metastasis for lung cancer. The “seed and soil” hypothesis
suggests that the bone marrow microenvironment (“soil”) may provide a conducive survival …
suggests that the bone marrow microenvironment (“soil”) may provide a conducive survival …
MCP-1 controls IL-17-promoted monocyte migration and M1 polarization in osteoarthritis
Osteoarthritis (OA) is a low-grade inflammatory joint illness in which monocytes migrate and
infiltrate synovial tissue, differentiating into the pro-inflammatory M1 macrophage phenotype …
infiltrate synovial tissue, differentiating into the pro-inflammatory M1 macrophage phenotype …
[HTML][HTML] Visfatin Facilitates VEGF-D-Induced Lymphangiogenesis through Activating HIF-1α and Suppressing miR-2277-3p in Human Chondrosarcoma
Chondrosarcoma is a malignant bone tumor that arises from abnormalities in cartilaginous
tissue and is associated with lung metastases. Lymphangiogenesis plays an essential role …
tissue and is associated with lung metastases. Lymphangiogenesis plays an essential role …
Hierarchical Microcarriers Loaded with Peptide Dendrimer‐Grafted Methotrexate for Rheumatoid Arthritis Treatment
Rheumatoid arthritis (RA) is one of the leading causes of disability due to the autoimmune
destruction of synovial joints. Great efforts have been put into developing multifunctional …
destruction of synovial joints. Great efforts have been put into developing multifunctional …
NGF facilitates ICAM-1-dependent monocyte adhesion and M1 macrophage polarization in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder in which
monocytes adhering to synovial tissue differentiate into the pro-inflammatory M1 …
monocytes adhering to synovial tissue differentiate into the pro-inflammatory M1 …