FTD spectrum: Neuroimaging across the FTD spectrum

JL Whitwell - Progress in molecular biology and translational …, 2019 - Elsevier
Frontotemporal dementia is a complex and heterogeneous neurodegenerative disease that
encompasses many clinical syndromes, pathological diseases, and genetic mutations …

Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's Disease

MF Mendez, I Nasir - Journal of Alzheimer's disease reports, 2023 - content.iospress.com
The differentiation of semantic variant primary progressive aphasia from dementia and
Alzheimer's disease can be difficult, particularly when the semantic anomia is pronounced …

The influence of β-amyloid on [18F]AV-1451 in semantic variant of primary progressive aphasia

JL Whitwell, PR Martin, JR Duffy, HM Clark… - Neurology, 2019 - AAN Enterprises
Objective To compare [18F] AV-1451 uptake in the semantic variant of primary progressive
aphasia (svPPA) to Alzheimer dementia, and determine whether increased uptake in svPPA …

Clinical features of late-onset semantic dementia

MF Mendez, D Chavez, RE Desarzant… - Cognitive and …, 2020 - journals.lww.com
Background: Semantic dementia (SD) is characterized by progressive semantic anomia
extending to a multimodal loss of semantic knowledge. Although often considered an early …

Two Rare Variants in PLAU and BACE1 Genes—Do They Contribute to Semantic Dementia Clinical Phenotype?

K Gaweda-Walerych, EJ Sitek, M Borczyk, M Berdyński… - Genes, 2021 - mdpi.com
We have performed whole-genome sequencing to identify the genetic variants potentially
contributing to the early-onset semantic dementia phenotype in a patient with family history …

Parietal involvement in the semantic variant of primary progressive aphasia with Alzheimer's disease cerebrospinal fluid profile

G Bera, R Migliaccio, T Michelin… - Journal of …, 2018 - content.iospress.com
Semantic variant of primary progressive aphasia (svPPA) is typically associated with non-
Alzheimer's disease (AD) pathology. However, some anatomopathological studies have …

Psilocybin to promote synaptogenesis in the brains of patients with mild cognitive impairment

J Song, Y Kambari, A Amaev, F Ueno, ET Carmona… - Medical …, 2023 - Elsevier
Amnestic mild cognitive impairment (aMCI) may represent a prodromal stage of Alzheimer's
disease dementia (ADD) for which there are no known treatments. There is renewed interest …

Positron emission tomography imaging biomarkers of frontotemporal dementia

MTM Clarke - 2023 - discovery.ucl.ac.uk
There are currently no disease modifying treatments available for frontotemporal dementia
(FTD). Pathological heterogeneity within and between FTD phenotypes and genotypes …

[PDF][PDF] Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's

MF Mendez, I Nasir - academia.edu
The differentiation of semantic variant primary progressive aphasia from dementia and
Alzheimer's disease can be difficult, particularly when the semantic anomia is pronounced …

Amyloid-positive late-onset semantic variant primary progressive aphasia

JS Lee, HY Rhee, KC Park - Neurological Sciences, 2018 - Springer
Dear Editor, Semantic variant primary progressive aphasia (svPPA), presenting loss of word
and object meanings with preserved fluent speech, is the one of three variants of primary …