[HTML][HTML] Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
MU Ferreira, TN de Sousa, GW Rangel… - International Journal for …, 2021 - Elsevier
Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics
C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …
especially the genomics, transcriptomics and proteomics branches, as technological tools …
Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …
Modeling the Dynamics of Plasmodium vivax Infection and Hypnozoite Reactivation In Vivo
AI Adekunle, M Pinkevych, R McGready… - PLoS neglected …, 2015 - journals.plos.org
The dynamics of Plasmodium vivax infection is characterized by reactivation of hypnozoites
at varying time intervals. The relative contribution of new P. vivax infection and reactivation …
at varying time intervals. The relative contribution of new P. vivax infection and reactivation …
Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses
ACR Silvino, GL Costa, FCF Araújo, DB Ascher… - PloS one, 2016 - journals.plos.org
Although Plasmodium vivax relapses are classically associated with hypnozoite activation, it
has been proposed that a proportion of these cases are due to primaquine (PQ) treatment …
has been proposed that a proportion of these cases are due to primaquine (PQ) treatment …
Micro-epidemiology and spatial heterogeneity of P. vivax parasitaemia in riverine communities of the Peruvian Amazon: A multilevel analysis
Malaria has steadily increased in the Peruvian Amazon over the last five years. This study
aimed to determine the parasite prevalence and micro-geographical heterogeneity of …
aimed to determine the parasite prevalence and micro-geographical heterogeneity of …
[HTML][HTML] Plasmodium vivax landscape in Brazil: scenario and challenges
AM Siqueira, O Mesones-Lapouble… - The American journal …, 2016 - ncbi.nlm.nih.gov
Brazil is the largest country of Latin America, with a considerable portion of its territoritory
within the malaria-endemic Amazon region in the North. Furthermore, a considerable portion …
within the malaria-endemic Amazon region in the North. Furthermore, a considerable portion …
Using Amplicon Deep Sequencing to Detect Genetic Signatures of Plasmodium vivax Relapse
Plasmodium vivax infections often recur due to relapse of hypnozoites from the liver. In
malaria-endemic areas, tools to distinguish relapse from reinfection are needed. We applied …
malaria-endemic areas, tools to distinguish relapse from reinfection are needed. We applied …
A High Resolution Case Study of a Patient with Recurrent Plasmodium vivax Infections Shows That Relapses Were Caused by Meiotic Siblings
AT Bright, MJ Manary, R Tewhey… - PLoS neglected …, 2014 - journals.plos.org
Plasmodium vivax infects a hundred million people annually and endangers 40% of the
world's population. Unlike Plasmodium falciparum, P. vivax parasites can persist as a …
world's population. Unlike Plasmodium falciparum, P. vivax parasites can persist as a …
Plasmodium vivax Diversity and Population Structure across Four Continents
Plasmodium vivax is the geographically most widespread human malaria parasite. To
analyze patterns of microsatellite diversity and population structure across countries of …
analyze patterns of microsatellite diversity and population structure across countries of …