The accumulation of an excessive amount of body fat can cause type 2 diabetes, and the
risk of type 2 diabetes increases linearly with an increase in body mass index. Accordingly …

Reassessing Human Adipose Tissue Adipose tissue can more than double in mass and
then return to baseline. This review discusses the functional roles of human white and brown …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

In rodents, obesity and aging impair nicotinamide adenine dinucleotide (NAD+)
biosynthesis, which contributes to metabolic dysfunction. Nicotinamide mononucleotide …

Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

BACKGROUND An increase in intrahepatic triglyceride (IHTG) is the hallmark feature of
nonalcoholic fatty liver disease (NAFLD) and is decreased by weight loss. Hepatic de novo …

Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

The prevalence of obesity, measured by body mass index, has risen to unacceptable levels
in both men and women in the United States and worldwide with resultant hazardous health …

Metabolic flexibility is the ability to respond or adapt to conditional changes in metabolic
demand. This broad concept has been propagated to explain insulin resistance and …

The current obesity epidemic poses a major public health issue since obesity predisposes
towards several chronic diseases. BMI and total adiposity are positively correlated with …