Obstructive sleep apnoea (OSA) is a heterogeneous and complex disease; however,
diagnosis and management still rely on a simple set of tools and few therapeutic options …

Abstract Purpose of the Review The main goal of this article is to discuss how the
development of state-of-the-art technology has made it possible to address fundamental …

Resistant hypertension is associated with an exceedingly high cardiovascular risk and there
remains an unmet therapeutic need driven by pathophysiologic pathways unaddressed by …

The pathophysiology of heart failure (HF) and hypertension are thought to involve brain
renin-angiotensin system (RAS) hyperactivity. Angiotensin III, a key effector peptide in the …

Abstract Purpose of Review To review the role and evidence for sympathetic overactivity in
resistant hypertension and review the therapies that have been studied to modulate the …

Resistant hypertension (RHTN), defined as an uncontrolled blood pressure despite the use
of multiple antihypertensive medications, is an increasing clinical problem associated with …

Diabetes mellitus (DM) is a growing epidemic. By 2030, it is projected that there will be at
least 400 million individuals with type 2 DM worldwide, with many of those affected being …

Работа выполнена с использованием комплекса современных клинико-
инструментальных методов исследования. Представлен разработанный авторами …

Abstract Purpose of Review To review the findings of trials evaluating pharmacological
treatment approaches for hypertension in general, and resistant hypertension (RH) in …

Background Hypertension is one of the major cardiovascular risk factors, closely related to
the major cardiovascular, neurological, and renal adverse events (1, 2). Resistant …