Background: Ischemic heart disease remains a leading cause of death worldwide. In this
study, we test the hypothesis that microRNA-210 protects the heart from myocardial …

Major advances in biomedical imaging have occurred over the last 2 decades and now
allow many physiological, cellular, and molecular processes to be imaged noninvasively in …

Background Heart failure (HF) with preserved ejection fraction (HFpEF) prevalence is
increasing, and large clinical trials have failed to reduce mortality. A major reason for this …

Longitudinal strain (LS) measured by echocardiography has been reported to be useful not
only for the diagnosis and risk stratification of various cardiac diseases, but also in cardio …

Background Traditional preclinical echocardiography (ECHO) modalities, including 1-
dimensional motion-mode (M-Mode) and 2-dimensional long axis (2D-US), rely on …

For the effective diagnosis of cardio vascular disease (CVD), anatomical characteristics of
the heart must be examined, which depends on segmenting the cardiac tissues of interest …

Significance: Cardiovascular disease is a major contributor to human mortality and
morbidity. The cardiac tissue undergoes fibrotic healing after injury because of the limited …

The left ventricular ejection fraction (LVEF) is one of the most commonly measured cardiac
parameters in echocardiography (echo). While the clinical guidelines suggest that apical …

Simple Summary Animal models reflecting the human situation as accurately as possible
are still essential to develop new therapies for diseases such as heart failure. The common …

Given that adverse remodeling is the leading cause of heart failure and death in the USA,
there is an urgent unmet need to develop new methods in dealing with this devastating …