Diversity of intervertebral disc cells: phenotype and function
The intervertebral disc (IVD) is a moderately moving joint that is located between the bony
vertebrae and provides flexibility and load transmission throughout the spinal column. The …
vertebrae and provides flexibility and load transmission throughout the spinal column. The …
[HTML][HTML] Notochordal cell-based treatment strategies and their potential in intervertebral disc regeneration
FC Bach, DW Poramba-Liyanage… - Frontiers in Cell and …, 2022 - frontiersin.org
Chronic low back pain is the number one cause of years lived with disability. In about 40% of
patients, chronic lower back pain is related to intervertebral disc (IVD) degeneration. The …
patients, chronic lower back pain is related to intervertebral disc (IVD) degeneration. The …
Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting
Low back pain is a major physical and socioeconomic problem. Degeneration of the
intervertebral disc and especially that of nucleus pulposus (NP) has been linked to low back …
intervertebral disc and especially that of nucleus pulposus (NP) has been linked to low back …
[HTML][HTML] Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and …
Introduction Currently, there is huge research focus on the development of novel cell-based
regeneration and tissue-engineering therapies for the treatment of intervertebral disc …
regeneration and tissue-engineering therapies for the treatment of intervertebral disc …
An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration
JE Frith, AR Cameron, DJ Menzies, P Ghosh… - Biomaterials, 2013 - Elsevier
Intervertebral disc (IVD) degeneration is one of the leading causes of lower back pain and a
major health problem worldwide. Current surgical treatments include excision or …
major health problem worldwide. Current surgical treatments include excision or …
Advancing cell therapies for intervertebral disc regeneration from the lab to the clinic: Recommendations of the ORS spine section
Intervertebral disc degeneration is strongly associated with chronic low back pain, a leading
cause of disability worldwide. Current back pain treatment approaches (both surgical and …
cause of disability worldwide. Current back pain treatment approaches (both surgical and …
[HTML][HTML] A review: Methodologies to promote the differentiation of mesenchymal stem cells for the regeneration of intervertebral disc cells following intervertebral disc …
T Ohnishi, K Homan, A Fukushima, D Ukeba, N Iwasaki… - Cells, 2023 - mdpi.com
Intervertebral disc (IVD) degeneration (IDD), a highly prevalent pathological condition
worldwide, is widely associated with back pain. Treatments available compensate for the …
worldwide, is widely associated with back pain. Treatments available compensate for the …
An update on animal models of intervertebral disc degeneration and low back pain: exploring the potential of artificial intelligence to improve research analysis and …
Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
[HTML][HTML] Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model
Introduction: As many as 80% of the adult population experience back pain at some point in
their lifetimes. Previous studies have indicated a link between back pain and intervertebral …
their lifetimes. Previous studies have indicated a link between back pain and intervertebral …
[HTML][HTML] De novo neo-hyaline-cartilage from bovine organoids in viscoelastic hydrogels
JF Crispim, K Ito - Acta Biomaterialia, 2021 - Elsevier
Regenerative therapies for articular cartilage are currently clinically available. However, they
are associated with several drawbacks that require resolution. Optimizing chondrocyte …
are associated with several drawbacks that require resolution. Optimizing chondrocyte …