Transcription factors and transporters in zinc homeostasis: lessons learned from fungi
DJ Eide - Critical reviews in biochemistry and molecular biology, 2020 - Taylor & Francis
Zinc is an essential nutrient for all organisms because this metal serves as a critical
structural or catalytic cofactor for many proteins. These zinc-dependent proteins are …
structural or catalytic cofactor for many proteins. These zinc-dependent proteins are …
Zinc sensing and regulation in yeast model systems
The Zap1 transcription factor of Saccharomyces cerevisiae and the Loz1 transcription factor
of Schizosaccharomyces pombe both play a central role in zinc homeostasis by controlling …
of Schizosaccharomyces pombe both play a central role in zinc homeostasis by controlling …
[HTML][HTML] The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast
Glycolysis and the pentose phosphate pathway both play a central role in the degradation of
glucose in all domains of life. Another metabolic route that can facilitate glucose breakdown …
glucose in all domains of life. Another metabolic route that can facilitate glucose breakdown …
[HTML][HTML] Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol
Zinc is an essential trace element that is required for the function of a large number of
proteins. As these zinc-binding proteins are found within the cytosol and organelles, all …
proteins. As these zinc-binding proteins are found within the cytosol and organelles, all …
Cellular sensing and transport of metal ions: implications in micronutrient homeostasis
AJ Bird - The Journal of nutritional biochemistry, 2015 - Elsevier
Micronutrients include the transition metal ions zinc, copper and iron. These metals are
essential for life as they serve as cofactors for many different proteins. On the other hand …
essential for life as they serve as cofactors for many different proteins. On the other hand …
A pathway for low zinc homeostasis that is conserved in animals and acts in parallel to the pathway for high zinc homeostasis
N Dietrich, DL Schneider, K Kornfeld - Nucleic acids research, 2017 - academic.oup.com
The essential element zinc plays critical roles in biology. High zinc homeostasis
mechanisms are beginning to be defined in animals, but low zinc homeostasis is poorly …
mechanisms are beginning to be defined in animals, but low zinc homeostasis is poorly …
[HTML][HTML] The nuclear receptor HIZR-1 uses zinc as a ligand to mediate homeostasis in response to high zinc
Nuclear receptors were originally defined as endocrine sensors in humans, leading to the
identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear …
identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear …
A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
Zinc is essential for biological systems, and aberrant zinc metabolism is implicated in a
broad range of human diseases. To maintain homeostasis in response to fluctuating levels …
broad range of human diseases. To maintain homeostasis in response to fluctuating levels …
Mechanisms of copper and zinc homeostasis in pathogenic black fungi
Black fungi comprise a diverse group of melanized microorganisms, many of which are able
to infect humans. One of the recognized diseases that arise with black fungi infection is …
to infect humans. One of the recognized diseases that arise with black fungi infection is …
Zinc homeostasis in Schizosaccharomyces pombe
R Yao, R Li, Y Huang - Archives of Microbiology, 2023 - Springer
Most metal ions such as iron, calcium, zinc, or copper are essential for all eukaryotes.
Organisms must maintain homeostasis of these metal ions because excess or deficiency of …
Organisms must maintain homeostasis of these metal ions because excess or deficiency of …