Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest
challenges facing cardiovascular medicine today. Despite being the most common form of …

Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

Heart failure is a consequence of various cardiovascular diseases and associated with poor
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …

RNA m6A modification is the most widely distributed RNA methylation and is closely related
to various pathophysiological processes. Although the benefit of regular exercise on the …

The roles and the underlying mechanisms of M1-type macrophages in angiogenesis and
postmyocardial infarction (MI) cardiac repair have remained unclear. In this study, we …

Despite significant improvements in reperfusion strategies, acute coronary syndromes all too
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …

In response to myocardial infarction (MI), cardiac macrophages regulate inflammation and
scar formation. We hypothesized that macrophages undergo polarization state changes over …

In 1993, the National Institutes of Health (NIH) enacted the Revitalization Act to establish
guidelines for inclusion of women and minorities in clinical research. In 2016, the NIH …

Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in
patients with coronary heart disease. Myocardial ischemia simultaneously induces …

Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …