Global virus outbreaks: Interferons as 1st responders

BX Wang, EN Fish - Seminars in immunology, 2019 - Elsevier
Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …

Extracellular vesicles in viral infections: two sides of the same coin?

ST Martins, LR Alves - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Extracellular vesicles are small membrane structures containing proteins and nucleic acids
that are gaining a lot of attention lately. They are produced by most cells and can be …

Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes

A Slonchak, LE Hugo, ME Freney… - Nature …, 2020 - nature.com
Flaviviruses, including Zika virus (ZIKV), utilise host mRNA degradation machinery to
produce subgenomic flaviviral RNA (sfRNA). In mammalian hosts, this noncoding RNA …

Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery

A Krishnan, P Gangadaran… - Experimental …, 2022 - journals.sagepub.com
The spread of SARS-CoV-2 over the entire world is more commonly known as COVID-19.
COVID-19 has impacted society in every aspect of routine life. SARS-CoV-2 infection is often …

Extracellular vesicles: roles in human viral infections, immune-diagnostic, and therapeutic applications

AO Ipinmoroti, QL Matthews - Pathogens, 2020 - mdpi.com
Membrane-bound vesicles that are released from cells are increasingly being studied as a
medium of intercellular communication, as these act to shuttle functional proteins, such as …

Extracellular vesicles regulated by viruses and antiviral strategies

L Yang, J Li, S Li, W Dang, S Xin, S Long… - Frontiers in cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs), consisting of exosomes, micro-vesicles, and other vesicles,
mainly originate from the multi-vesicular body (MVB) pathway or plasma membrane. EVs are …

Feasibility of tumor‑derived exosome enrichment in the onco‑hematology leukemic model of chronic myeloid leukemia

S Bernardi, C Foroni, C Zanaglio… - International …, 2019 - spandidos-publications.com
Due to the discovery of their role in intra‑cellular communications, exosomes, which carry
information specific to the cell of origin, have garnered considerable attention in cancer …

Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections

S Lane, TLA White, EE Walsh, RT Cattley… - Mbio, 2023 - Am Soc Microbiol
Extracellular vesicles (EVs) are produced by most known cell types as a form of intercellular
communication to influence the physiological function of neighboring cells. During …

The regulation of flavivirus infection by hijacking exosome-mediated cell–cell communication: new insights on virus–host interactions

JM Reyes-Ruiz, JF Osuna-Ramos… - Viruses, 2020 - mdpi.com
The arthropod-borne flaviviruses are important human pathogens, and a deeper
understanding of the virus–host cell interaction is required to identify cellular targets that can …

Noncoding RNA of Zika Virus Affects Interplay between Wnt-Signaling and Pro-Apoptotic Pathways in the Developing Brain Tissue

A Slonchak, H Chaggar, J Aguado, E Wolvetang… - Viruses, 2023 - mdpi.com
Zika virus (ZIKV) has a unique ability among flaviviruses to cross the placental barrier and
infect the fetal brain causing severe abnormalities of neurodevelopment known collectively …