Believing in black boxes: machine learning for healthcare does not need explainability to be evidence-based

LG McCoy, CTA Brenna, SS Chen, K Vold… - Journal of clinical …, 2022 - Elsevier
Objective To examine the role of explainability in machine learning for healthcare (MLHC),
and its necessity and significance with respect to effective and ethical MLHC application …

[HTML][HTML] Mitochondria and T2D: role of autophagy, ER stress, and inflammasome

M Rocha, N Apostolova, R Diaz-Rua, J Muntane… - Trends in Endocrinology …, 2020 - cell.com
Type 2 diabetes (T2D) is one of the main current threats to human health. Both T2D and its
numerous clinical complications are related to mitochondrial dysfunction and oxidative …

Low-Carbohydrate diets in the management of obesity and type 2 diabetes: a review from clinicians using the approach in practice

T Kelly, D Unwin, F Finucane - International journal of environmental …, 2020 - mdpi.com
Low-carbohydrate diets are increasingly used to help patients with obesity and type 2
diabetes. We sought to provide an overview of the evidence for this treatment approach …

Anti-inflammatory strategies targeting metaflammation in type 2 diabetes

A Kuryłowicz, K Koźniewski - Molecules, 2020 - mdpi.com
One of the concepts explaining the coincidence of obesity and type 2 diabetes (T2D) is the
metaflammation theory. This chronic, low-grade inflammatory state originating from …

Precision nutrition in the context of bariatric surgery

M Aguas-Ayesa, P Yárnoz-Esquíroz, L Olazarán… - Reviews in Endocrine …, 2023 - Springer
Bariatric surgery (BS) is the most effective long-term treatment for severe obesity. This
review summarizes the main nutritional deficiencies before and after BS, as well as current …

Do gut hormones contribute to weight loss and glycaemic outcomes after bariatric surgery?

D Papamargaritis, CW le Roux - Nutrients, 2021 - mdpi.com
Bariatric surgery is an effective intervention for management of obesity through treating
dysregulated appetite and achieving long-term weight loss maintenance. Moreover …

The role of diabetes severity scores in predicting disease remission in patients with BMI > 50 kg/m2 undergoing Roux-En-Y gastric bypass and sleeve gastrectomy …

W Ghusn, P Ma, K Ikemiya, K Hage, DM Abboud… - Surgical …, 2023 - Springer
Abstract Background Roux-En-Y gastric bypass (RYGB) and Sleeve Gastrectomy (SG) have
shown to be two of the most effective interventions to enhance weight loss and associated …

Type-2 diabetes mellitus remission prediction models after Roux-En-Y gastric bypass and sleeve gastrectomy based on disease severity scores

W Ghusn, K Hage, RA Vierkant… - Diabetes Research and …, 2024 - Elsevier
Aim Metabolic and bariatric surgery (MBS) is considered one of the most effective
interventions for weight loss and associated type-2 diabetes mellitus (T2DM) remission …

Remission as an emerging therapeutic target in type 2 diabetes in the era of New glucose-lowering agents: Benefits, challenges, and treatment approaches

D Vasdeki, T Koufakis, G Tsamos, L Busetto… - Nutrients, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a progressive disease with a growing prevalence,
associated with an increased risk of complications. The introduction of new classes of …

Sleeve gastrectomy causes weight‐loss independent improvements in hepatic steatosis

ER McGlone, M Siebert, M Dore, DCD Hope… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Sleeve gastrectomy (VSG) leads to improvement in hepatic
steatosis, associated with weight loss. The aims of this study were to investigate whether …