Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
Endophytic fungi—alternative sources of cytotoxic compounds: a review
Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …
reported annually. The elevated rate of mortality necessitates a global challenge to explore …
Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …
important mode of chemical transformations and are expected to become a crucial field at …
Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases
MD Ferrer, C Busquets-Cortés, X Capó… - Current medicinal …, 2019 - ingentaconnect.com
Inflammation plays a crucial role in the development of many complex diseases and
disorders including autoimmune diseases, metabolic syndrome, neurodegenerative …
disorders including autoimmune diseases, metabolic syndrome, neurodegenerative …
A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …
recent years, different heterocyclic derivatives have been designed to counter the infections …
Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients
AY Sukhorukov, AA Sukhanova, SG Zlotin - Tetrahedron, 2016 - Elsevier
Nitroalkanes and nitroalkenes have been always considered as convenient and readily
available intermediates in organic synthesis, including total synthesis of natural products. 1 …
available intermediates in organic synthesis, including total synthesis of natural products. 1 …
Medicinal chemistry of oxazines as promising agents in drug discovery
Oxazines have brought much synthetic interest due to their extensive biological activities.
These are the important category of heterocycles, which may be formally derived from …
These are the important category of heterocycles, which may be formally derived from …
Targeting heparanase in cancer: inhibition by synthetic, chemically modified, and natural compounds
CD Mohan, S Hari, HD Preetham, S Rangappa… - Iscience, 2019 - cell.com
Heparanase is an endoglycosidase involved in remodeling the extracellular matrix and
thereby in regulating multiple cellular processes and biological activities. It cleaves heparan …
thereby in regulating multiple cellular processes and biological activities. It cleaves heparan …