Emerging SARS-CoV-2 resistance after antiviral treatment
TJ Tamura, MC Choudhary, R Deo, F Yousuf… - JAMA Network …, 2024 - jamanetwork.com
Importance Previous studies have identified mutations in SARS-CoV-2 strains that confer
resistance to nirmatrelvir, yet how often this resistance arises and its association with …
resistance to nirmatrelvir, yet how often this resistance arises and its association with …
Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections
SJ Hurwitz, R De, JC LeCher, JA Downs-Bowen… - Viruses, 2024 - mdpi.com
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …
Phytoconstituents of Citrus limon (Lemon) as Potential Inhibitors Against Multi Targets of SARS-CoV-2 by Use of Molecular Modelling and In Vitro Determination …
K Raman, R Kalirajan, F Islam, S Jupudi… - …, 2024 - Wiley Online Library
In the present work, phytoconstituents from Citrus limon are computationally tested against
SARS-CoV-2 target protein such as Mpro-(5R82. pdb), Spike-(6YZ5. pdb) &RdRp-(7BTF …
SARS-CoV-2 target protein such as Mpro-(5R82. pdb), Spike-(6YZ5. pdb) &RdRp-(7BTF …