Practical relevance: Increases in cat ownership worldwide mean more cats are requiring
veterinary care. Illness, trauma and surgery can result in acute pain, and effective …

Pain affects feline health and welfare. As the fourth vital sign, it must always be assessed in
every physical examination. Knowledge of feline pain management has grown greatly. The …

Opiates have a long history of medical use as effective analgesics associated with well‐
described side effects, including euphoria, respiratory depression, constipation, bradycardia …

A novel transdermal buprenorphine solution (TBS) was developed for evaluation in order to
make available an extended duration opioid analgesic for cats. Healthy adult cats were …

Purpose Combination therapy is a promising strategy to treat cancer due to the synergistic
effects. The drug and gene co-delivered systems attract more attention in the field of …

Background Buprenorphine is one of the most used analgesics for postoperative pain in
rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for intravenous …

Pain management in rabbits can be difficult because they are adept at hiding pain and can
be stressed by handling and restraint for injection. The use of opioid analgesics with …

Background Buprenorphine is a potent lipophilic opioid analgesic that is largely used in the
multimodal treatment of acute pain. Simbadol (buprenorphine hydrochloride) is the first and …

Background Buprenorphine is used for canine postoperative pain management. This study
aimed to describe the pharmacokinetics and evaluate the analgesic efficacy of …

A prospective, double masked, placebo‐controlled, multicentered phase 3 clinical study was
conducted to evaluate the safety and effectiveness of transdermal buprenorphine solution …