Intracellular parasites of the phylum Apicomplexa harbor a plastid-like organelle called
apicoplast that is the most reduced organelle of this type known. Due to the medical …

The malaria parasite‐infected erythrocyte is a multi‐compartment structure, incorporating
numerous different membrane systems. The movement of nutrients, metabolites and …

Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …

Malaria parasites evade immune detection by growth and replication within erythrocytes.
After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of …

The malaria agent Plasmodium falciparum is predicted to export a “secretome” of several
hundred proteins to remodel the host erythrocyte. Prediction of protein export is based on …

The most severe form of human malaria is caused by Plasmodium falciparum. Its virulence is
closely linked to the increase in rigidity of infected erythrocytes and their adhesion to …

The asexual reproduction cycle of Plasmodium falciparum, the parasite responsible for
severe malaria, occurs within red blood cells. A merozoite invades a red cell in the …

Malaria parasites activate a broad-selectivity ion channel on their host erythrocyte
membrane to obtain essential nutrients from the bloodstream. This conserved channel …

Red blood cell research is important for both, the clinical haematology, such as transfusion
medicine or anaemia investigations, and the basic research fields like exploring general …

Background Modulation of infected host cells by intracellular pathogens is a prerequisite for
successful establishment of infection. In the human malaria parasite Plasmodium falciparum …