Olea europaea L-derived secoiridoids: Beneficial health effects and potential therapeutic approaches

S Filardo, M Roberto, D Di Risola, L Mosca… - Pharmacology & …, 2024 - Elsevier
Over the years, health challenges have become increasingly complex and global and, at the
beginning of the 21st century, chronic diseases, including cardiovascular, neurological, and …

Role of hydroxytyrosol and oleuropein in the prevention of aging and related disorders: focus on neurodegeneration, skeletal muscle dysfunction and gut microbiota

L Micheli, L Bertini, A Bonato, N Villanova, C Caruso… - Nutrients, 2023 - mdpi.com
Aging is a multi-faceted process caused by the accumulation of cellular damage over time,
associated with a gradual reduction of physiological activities in cells and organs. This …

Effects of hydroxytyrosol in endothelial functioning: a comprehensive review

U Vijakumaran, J Shanmugam, JW Heng, SS Azman… - Molecules, 2023 - mdpi.com
Pharmacologists have been emphasizing and applying plant and herbal-based treatments
in vascular diseases for decades now. Olives, for example, are a traditional symbol of the …

Effects of dietary supplementation of a resin-purified aqueous-isopropanol olive leaf extract on meat and liver antioxidant parameters in broilers

K Vasilopoulou, GA Papadopoulos, S Lioliopoulou… - Antioxidants, 2023 - mdpi.com
Olive leaves are byproducts οf the agro-industrial sector and are rich in bioactive
compounds with antioxidant properties. They could be supplemented in poultry diets …

Metabolomic-based studies of the intake of virgin olive oil: a comprehensive review

A Vazquez-Aguilar, E Sanchez-Rodriguez… - Metabolites, 2023 - mdpi.com
Virgin olive oil (VOO) is a high-value product from the Mediterranean diet. Some health and
nutritional benefits have been associated with its consumption, not only because of its …

Pretreatment with oleuropein protects the neonatal brain from hypoxia-ischemia by inhibiting apoptosis and neuroinflammation

M Reyes-Corral, L Gil-González… - Journal of Cerebral …, 2024 - journals.sagepub.com
Hypoxic-ischemic (HI) encephalopathy is a cerebrovascular injury caused by oxygen
deprivation to the brain and remains a major cause of neonatal mortality and morbidity …

Olive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease

JF García-Gavilán, N Babio, E Toledo… - Cardiovascular …, 2023 - Springer
Background Olive oil consumption has been inversely associated with the risk of type 2
diabetes (T2D) and cardiovascular disease (CVD). However, the impact of olive oil …

Anti-inflammatory effects of nutritionally relevant concentrations of oleuropein and hydroxytyrosol on peripheral blood mononuclear cells: an age-related analysis

F Pojero, F Gervasi, SD Fiore, A Aiello… - International Journal of …, 2023 - mdpi.com
Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The
Mediterranean diet is a non-invasive intervention to improve the chronic low-grade …

Oxidized-multiwalled carbon nanotubes as non-toxic nanocarriers for hydroxytyrosol delivery in cells

P Zygouri, AM Athinodorou, K Spyrou, YV Simos… - Nanomaterials, 2023 - mdpi.com
Carbon nanotubes (CNTs) possess excellent physicochemical and structural properties
alongside their nano dimensions, constituting a medical platform for the delivery of different …

[HTML][HTML] Unraveling the Protective Role of Oleocanthal and Its Oxidation Product, Oleocanthalic Acid, against Neuroinflammation

MC Barbalace, M Freschi, I Rinaldi, L Zallocco… - Antioxidants, 2024 - mdpi.com
Neuroinflammation is a critical aspect of various neurodegenerative diseases, such as
Alzheimer's and Parkinson's diseases. This study investigates the anti-neuroinflammatory …