Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach
S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …
biological activity via binding to a promoter region in the nucleus and transcribing various …
[HTML][HTML] Methamphetamine-induced neuronal damage: neurotoxicity and neuroinflammation
B Kim, J Yun, B Park - Biomolecules & therapeutics, 2020 - ncbi.nlm.nih.gov
Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …
Microglia in neuroimmunopharmacology and drug addiction
H Li, LR Watkins, X Wang - Molecular Psychiatry, 2024 - nature.com
Drug addiction is a chronic and debilitating disease that is considered a global health
problem. Various cell types in the brain are involved in the progression of drug addiction …
problem. Various cell types in the brain are involved in the progression of drug addiction …
THC and CBD: villain versus hero? Insights into adolescent exposure
Cannabis is the most used drug of abuse worldwide. It is well established that the most
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …
[HTML][HTML] Herbal bioactives in treatment of inflammation: An overview
Background Inflammation, an important event of cellular defensive system, can be triggered
by a variety of factors such as pathogens, allergens, damaged cells and toxic compounds …
by a variety of factors such as pathogens, allergens, damaged cells and toxic compounds …
[HTML][HTML] Lipopolysaccharide induced altered signaling pathways in various neurological disorders
Neuroinflammation is defined as an inflammatory response within the brain or spinal cord,
whereas the brain's innate immune system is triggered by various inflammatory challenges …
whereas the brain's innate immune system is triggered by various inflammatory challenges …
Cancer Initiation, Progression and Resistance: Are Phytocannabinoids from Cannabis sativa L. Promising Compounds?
Cannabis sativa L. is a source of over 150 active compounds known as phytocannabinoids
that are receiving renewed interest due to their diverse pharmacologic activities. Indeed …
that are receiving renewed interest due to their diverse pharmacologic activities. Indeed …
The common denominators of Parkinson's disease pathogenesis and methamphetamine abuse
B Vincent, M Shukla - Current Neuropharmacology, 2024 - benthamdirect.com
The pervasiveness and mortality associated with methamphetamine abuse have doubled
during the past decade, suggesting a possible worldwide substance use crisis. Epitomizing …
during the past decade, suggesting a possible worldwide substance use crisis. Epitomizing …
Cannabidiol reduces short-and long-term high glutamate release after severe traumatic brain injury and improves functional recovery
C Santiago-Castañeda, S Huerta de la Cruz… - Pharmaceutics, 2022 - mdpi.com
This study aimed to determine if orally administered cannabidiol (CBD) lessens the cortical
over-release of glutamate induced by a severe traumatic brain injury (TBI) and facilitates …
over-release of glutamate induced by a severe traumatic brain injury (TBI) and facilitates …
[HTML][HTML] Multi-targeting inulin-based nanoparticles with cannabidiol for effective prevention of ulcerative colitis
X Zhang, X Gao, X Yi, H Yu, M Shao, Y Li, X Shen - Materials Today Bio, 2024 - Elsevier
The pathogenesis of ulcerative colitis (UC) is closely related to severe inflammation,
damaged colonic mucosal barrier, increased oxidative stress and intestinal ecological …
damaged colonic mucosal barrier, increased oxidative stress and intestinal ecological …