Before it was molecularly cloned in 1994, acute-phase response factor or signal transducer
and activator of transcription (STAT) 3 was the focus of intense research into understanding …

The prevalence of overweight and obesity is on the rise around the world. Common
comorbidities associated with obesity, particularly diabetes, hypertension, and heart disease …

Fumaric acid esters (FAEs) such as dimethylfumarate (DMF) are used for the treatment of
adults with moderate‐to‐severe psoriasis. The mode of action of FAEs is complex. Here, we …

Objectives Whether periodic oral intake of postbiotics positively affects weight regulation and
prevents obesity‐associated diseases in vivo is unclear. This study evaluated the action …

Bioactivities of fish collagen peptide are now being elucidated in diverse biological systems.
Here, we investigated the effect of fish collagen peptide on the adipogenic differentiation of …

Metabolic reprogramming during macrophage polarization supports the effector functions of
these cells in health and disease. Here, we demonstrate that pyruvate dehydrogenase …

Objective Chronic low-grade inflammation has long been recognized as the central link
between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22 …

The flower of Inula britannica contains various phenolic compounds with prophylactic
properties. This study aimed to determine the anti-adipogenic effect of an I. britannica flower …

JAK-STAT signaling pathway plays an important role in the cells' development and
homeostasis. Over the past decades, the studies have identified the role of the JAK-STAT …

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that has
recently attracted increased attention. Accumulating studies have demonstrated that STAT3 …