Metagenomics: An effective approach for exploring microbial diversity and functions

NN Nam, HDK Do, KT Loan Trinh, NY Lee - Foods, 2023 - mdpi.com
Various fields have been identified in the “omics” era, such as genomics, proteomics,
transcriptomics, metabolomics, phenomics, and metagenomics. Among these …

The indoors microbiome and human health

JA Gilbert, EM Hartmann - Nature Reviews Microbiology, 2024 - nature.com
Indoor environments serve as habitat for humans and are replete with various reservoirs and
niches for microorganisms. Microorganisms enter indoor spaces with their human and non …

Evaluation of taxonomic classification and profiling methods for long-read shotgun metagenomic sequencing datasets

DM Portik, CT Brown, NT Pierce-Ward - BMC bioinformatics, 2022 - Springer
Background Long-read shotgun metagenomic sequencing is gaining in popularity and offers
many advantages over short-read sequencing. The higher information content in long reads …

Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions

J Chen, SL Siliceo, Y Ni, HB Nielsen, A Xu… - Microbiome, 2023 - Springer
Background A growing body of evidence suggests that the gut microbiota is strongly linked
to general human health. Microbiome-directed interventions, such as diet and exercise, are …

Metagenomic assessment of gut microbial communities and risk of severe COVID-19

LH Nguyen, D Okin, DA Drew, VM Battista… - Genome Medicine, 2023 - Springer
Background The gut microbiome is a critical modulator of host immunity and is linked to the
immune response to respiratory viral infections. However, few studies have gone beyond …

The standardisation of the approach to metagenomic human gut analysis: from sample collection to microbiome profiling

N Szóstak, A Szymanek, J Havránek, K Tomela… - Scientific Reports, 2022 - nature.com
In recent years, the number of metagenomic studies increased significantly. Wide range of
factors, including the tremendous community complexity and variability, is contributing to the …

Recovering prokaryotic genomes from host-associated, short-read shotgun metagenomic sequencing data

S Saheb Kashaf, A Almeida, JA Segre, RD Finn - Nature protocols, 2021 - nature.com
Recovering genomes from shotgun metagenomic sequence data allows detailed taxonomic
and functional characterization of individual species or strains in a microbial community …

Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data

O Aizpurua, RR Dunn, LH Hansen… - Critical Reviews in …, 2024 - Taylor & Francis
Shotgun metagenomics is an increasingly cost-effective approach for profiling
environmental and host-associated microbial communities. However, due to the complexity …

Characterization and demonstration of mock communities as control reagents for accurate human microbiome community measurements

DM Tourlousse, K Narita, T Miura, A Ohashi… - Microbiology …, 2022 - Am Soc Microbiol
Standardization and quality assurance of microbiome community analysis by high-
throughput DNA sequencing require widely accessible and well-characterized reference …

The environmental microbiome, allergic disease, and asthma

MS Kelly, S Bunyavanich, W Phipatanakul… - The Journal of Allergy and …, 2022 - Elsevier
The environmental microbiome represents the entirety of the microbes and their metabolites
that we encounter in our environments. A growing body of evidence supports the role of the …