Advantages and limitations of the neonatal immune system

GP Tsafaras, P Ntontsi, G Xanthou - Frontiers in pediatrics, 2020 - frontiersin.org
During early post-natal life, neonates must adjust to the transition from the sheltered intra-
uterine environment to the microbe-laden external world, wherein they encounter a …

Association of peripheral blood levels of cytokines with autism spectrum disorder: A meta-analysis

H Zhao, H Zhang, S Liu, W Luo, Y Jiang… - Frontiers in psychiatry, 2021 - frontiersin.org
Background: Although increasing evidence suggests an association between alterations in
peripheral cytokines and autism spectrum disorder (ASD), a consensus is lacking. To …

Biomarkers in autism spectrum disorders: Current progress

L Shen, XK Liu, H Zhang, J Lin, C Feng, J Iqbal - Clinica Chimica Acta, 2020 - Elsevier
Autism spectrum disorder (ASD) refers to a group of complex neurodevelopmental disorders
characterized by social interaction and communication deficits and repetitive and …

Early life environmental factors associated with autism spectrum disorder symptoms in children at age 2 years: a birth cohort study

C Pham, C Symeonides, M O'Hely, PD Sly… - …, 2022 - journals.sagepub.com
Mounting evidence finds that early life environmental factors increased the probability of
autism spectrum disorder. We estimated prospective associations between early life …

Immunoregulatory and/or anti-inflammatory agents for the management of core and associated symptoms in individuals with autism spectrum disorder: A narrative …

G Arteaga-Henriquez, L Gisbert, JA Ramos-Quiroga - CNS drugs, 2023 - Springer
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with a
so far poorly understood underlying pathogenesis, and few effective therapies for core …

[HTML][HTML] Novel treatments for autism spectrum disorder based on genomics and systems biology

D Baribeau, E Anagnostou - Pharmacology & therapeutics, 2022 - Elsevier
Background Autism spectrum disorder (ASD) is a highly heterogeneous
neurodevelopmental disorder with a complex underlying genetic architecture. There are …

Activation of the monocyte/macrophage system and abnormal blood levels of lymphocyte subpopulations in individuals with autism spectrum disorder: A systematic …

G Arteaga-Henríquez, J Lugo-Marín, L Gisbert… - International journal of …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition with a so far unknown
etiology. Increasing evidence suggests that a state of systemic low-grade inflammation may …

Comprehensive immunoprofiling of neurodevelopmental disorders suggests three distinct classes based on increased neurogenesis, Th-1 polarization or IL-1 …

N Sreenivas, M Maes, H Padmanabha… - Brain, Behavior, and …, 2024 - Elsevier
Neurodevelopmental disorders (NDDs) are a spectrum of conditions with commonalities as
well as differences in terms of phenome, symptomatome, neuropathology, risk factors and …

[HTML][HTML] TH1/Treg ratio may be a marker of autism in children with immune dysfunction

ZQ Nie, D Han, K Zhang, M Li, HK Kwon, SH Im… - Research in Autism …, 2023 - Elsevier
Evidence suggests a link between autism spectrum disorder (ASD), behavioral symptoms in
the context of ASD, and presence of an altered immune function. Several studies have …

Altered cytokine levels in the cerebrospinal fluid of adult patients with autism spectrum disorder

K Runge, BL Fiebich, H Kuzior, J Rausch… - Journal of Psychiatric …, 2023 - Elsevier
Background Despite intensive research, the etiological causes of autism spectrum disorder
(ASD) remain elusive. Immunological mechanisms have recently been studied more …