The biomechanical signature of loss of consciousness: computational modelling of elite athlete head injuries
Sports related head injuries can cause transient neurological events including loss of
consciousness and dystonic posturing. However, it is unknown why head impacts that …
consciousness and dystonic posturing. However, it is unknown why head impacts that …
The benefits of exercise for outcome improvement following traumatic brain injury: Evidence, pitfalls and future perspectives
Y Zhang, Z Huang, H Xia, J Xiong, X Ma, C Liu - Experimental Neurology, 2022 - Elsevier
Traumatic brain injury (TBI), also known as a silent epidemic, is currently a substantial public
health problem worldwide. Given the increased energy demands following brain injury …
health problem worldwide. Given the increased energy demands following brain injury …
[HTML][HTML] Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …
families, the search for new therapies has been a source of hope and frustration. Almost all …
Detecting axonal injury in individual patients after traumatic brain injury
AE Jolly, M Bălăeţ, A Azor, D Friedland, S Sandrone… - Brain, 2021 - academic.oup.com
Poor outcomes after traumatic brain injury (TBI) are common yet remain difficult to predict.
Diffuse axonal injury is important for outcomes, but its assessment remains limited in the …
Diffuse axonal injury is important for outcomes, but its assessment remains limited in the …
Distinct patterns of structural damage underlie working memory and reasoning deficits after traumatic brain injury
It is well established that chronic cognitive problems after traumatic brain injury relate to
diffuse axonal injury and the consequent widespread disruption of brain connectivity …
diffuse axonal injury and the consequent widespread disruption of brain connectivity …
[HTML][HTML] Neuroradiological changes following single or repetitive mild TBI
P Kulkarni, TR Morrison, X Cai, S Iriah… - Frontiers in systems …, 2019 - frontiersin.org
Objectives To test the hypothesis that there are differences in neuroradiological measures
between single and repeated mild traumatic brain injury using multimodal MRI. Methods A …
between single and repeated mild traumatic brain injury using multimodal MRI. Methods A …
Stratifying drug treatment of cognitive impairments after traumatic brain injury using neuroimaging
Cognitive impairment is common following traumatic brain injury. Dopaminergic drugs can
enhance cognition after traumatic brain injury, but individual responses are highly variable …
enhance cognition after traumatic brain injury, but individual responses are highly variable …
N6-methyladenosine RNA modification: a promising regulator in central nervous system injury
Q Wang, Y Liang, X Luo, Y Liu, X Zhang, L Gao - Experimental Neurology, 2021 - Elsevier
In addition to DNA methylation, reversible epigenetic modification occurring in RNA has
been discovered recently. The most abundant type of RNA methylation is N6 …
been discovered recently. The most abundant type of RNA methylation is N6 …
Paths to successful translation of new therapies for severe traumatic brain injury in the golden age of traumatic brain injury research: a Pittsburgh vision
PM Kochanek, TC Jackson, RM Jha… - Journal of …, 2020 - liebertpub.com
New neuroprotective therapies for severe traumatic brain injury (TBI) have not translated
from pre-clinical to clinical success. Numerous explanations have been suggested in both …
from pre-clinical to clinical success. Numerous explanations have been suggested in both …
[HTML][HTML] Approaches to monitor circuit disruption after traumatic brain injury: frontiers in preclinical research
G Krishna, JA Beitchman, CE Bromberg… - International journal of …, 2020 - mdpi.com
Mild traumatic brain injury (TBI) often results in pathophysiological damage that can manifest
as both acute and chronic neurological deficits. In an attempt to repair and reconnect …
as both acute and chronic neurological deficits. In an attempt to repair and reconnect …