Hyaluronic acid (HA) is of immense importance to biomaterials science and biomedical
engineering. It is finding applications in diverse areas of bioengineering ranging from …

Background Worldwide, many people suffer from knee injuries and articular cartilage
damage every year, which causes pain and reduces productivity, life quality, and daily …

In the synovial joint, mechanical force creates an important signal that influences
chondrocyte behavior. The conversion of mechanical signals into biochemical cues relies on …

Tissue engineering holds great promise in the generation of cartilage analogues for
cartilage injury repair and replacement. However, for a long time, a variety of issues have …

The degradation of cartilage, due to trauma, mechanical load or diseases, results in
abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA) …

Since cartilage has a limited capacity for self-regeneration, treating cartilage degenerative
disorders is a long-standing difficulty in orthopedic medicine. Researchers have scrutinized …

Electrical stimulation (ES) has been frequently used in different biomedical applications both
in vitro and in vivo. Numerous studies have demonstrated positive effects of ES on cellular …

Articular cartilage defects represent an unsolved clinical challenge. Photopolymerizable
hydrogels are attractive candidates supporting repair. This study investigates the short‐term …

Articular cartilage is vulnerable to mechanical overload and has limited ability to restore
lesions, which leads to the development of chronic diseases such as osteoarthritis (OA). In …

The unique structure and composition of articular cartilage is critical for its physiological
function. However, this architecture may get disrupted by degeneration or trauma. Due to the …