Terpenoids form the most diversified class of natural products, which have gained
application in the pharmaceutical, food, transportation, and fine and bulk chemical …

Recombinant protein production for medical, academic, or industrial applications is essential
for our current life. Recombinant proteins are obtained mainly through microbial …

Optimization and monitoring of bioprocesses requires the measurement of several process
parameters and quality attributes. Mass spectrometry (MS)‐based techniques such as those …

The combination of Escherichia coli BL21 (DE3) and the pET expression system is used
extensively for the expression of various recombinant proteins (RPs). However, RP …

To investigate the metabolic elasticity and production bottlenecks for recombinant silk
proteins in Escherichia coli, we performed a comprehensive characterization of one elastin …

As the biopharmaceutical industry looks to implement Industry 4.0, the need for rapid and
robust analytical characterization of analytes has become a pressing priority. Spectroscopic …

L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and
feed industries. Microbial fermentation is the most commonly used method to produce L …

The use of short peptide tags in synthetic genetic circuits allows for the tuning of gene
expression dynamics and release of amino acid resources through targeted protein …

Dynamic flux balance analysis (FBA) allows estimation of intracellular reaction rates using
organism‐specific genome‐scale metabolic models (GSMM) and by assuming …

The overproduction of recombinant proteins in Escherichia coli leads to insoluble
aggregates of proteins called inclusion bodies (IBs). IBs are considered dynamic entities that …