The ubiquitin codes in cellular stress responses

X Sheng, Z Xia, H Yang, R Hu - Protein & cell, 2024 - academic.oup.com
Ubiquitination/ubiquitylation, one of the most fundamental post-translational modifications,
regulates almost every critical cellular process in eukaryotes. Emerging evidence has shown …

Ions, the movement of water and the apoptotic volume decrease

CD Bortner, JA Cidlowski - Frontiers in cell and developmental …, 2020 - frontiersin.org
The movement of water across the cell membrane is a natural biological process that occurs
during growth, cell division, and cell death. Many cells are known to regulate changes in …

lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca2+ overload in myocardial infarction mice model

L Jiao, M Li, Y Shao, Y Zhang, M Gong, X Yang… - Cell death & …, 2019 - nature.com
Previously, we have identified ZFAS1 as a potential new long non-coding RNA (lncRNA)
biomarker of acute myocardial infarction (MI) and as a sarcoplasmic reticulum Ca2+-ATPase …

[HTML][HTML] Oxytocin ameliorates high glucose-and ischemia/reperfusion-induced myocardial injury by suppressing pyroptosis via AMPK signaling pathway

M Yao, Z Wang, L Jiang, L Wang, Y Yang… - Biomedicine & …, 2022 - Elsevier
The present study aimed to explore the role of oxytocin (OT) in myocardial injury induced by
ischemia/reperfusion (I/R) and hyperglycemia and its underlying mechanisms. In this study …

Potentially detrimental effects of hyperosmolality in patients treated for traumatic brain injury

W Dabrowski, D Siwicka-Gieroba, C Robba… - Journal of clinical …, 2021 - mdpi.com
Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain
injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in …

The P5-type ATPase Spf1 is required for development and virulence of the rice blast fungus Pyricularia oryzae

Y Qu, J Wang, X Zhu, B Dong, X Liu, J Lu, F Lin - Current Genetics, 2020 - Springer
Pyricularia oryzae (synonym Magnaporthe oryzae) is a plant pathogen causing major yield
losses in cultivated rice and wheat. The P-type ATPases play important roles in cellular …

Betaine ameliorates impaired steroidogenesis and apoptosis in mice granulosa cells induced by high glucose concentration

KA Samie, MR Tabandeh, M Afrough - Systems biology in …, 2020 - Taylor & Francis
Betaine is a bioactive peptide whose beneficial effects on diabetes complications have been
considered, previously. The present study aimed to investigate the possible protective …

Baicalein facilitates gastric cancer cell apoptosis by triggering endoplasmic reticulum stress via repression of the PI3K/AKT pathway

J Shen, Z Yang, X Wu, G Yao, M Hou - Applied Biological Chemistry, 2023 - Springer
Objective Gastric cancer (GC) remains a prevailing threat to life. Baicalein exhibits anti-
cancer properties. This study estimated the mechanism of baicalein in GC cell apoptosis by …

Ouabain-Induced Cell Death and Survival. Role of α1-Na,K-ATPase-Mediated Signaling and [Na+]i/[K+]i-Dependent Gene Expression

OD Lopina, AM Tverskoi, EA Klimanova… - Frontiers in …, 2020 - frontiersin.org
Ouabain is of cardiotonic steroids (CTS) family that is plant-derived compounds and is
known for many years as therapeutic and cytotoxic agents. They are specific inhibitors of Na …

LncRNA HOTTIP knockdown attenuates acute myocardial infarction via regulating miR-92a-2/c-Met axis

B Wang, L Ma, J Wang - Cardiovascular Toxicology, 2022 - Springer
Increasing investigations have focused on long non-coding RNAs (lncRNAs) in various
human diseases, including acute myocardial infarction (AMI). Although lncRNA HOTTIP has …