A new scientific frontier opened in 2009 with the start of operations of the world's first x-ray
free-electron laser (FEL), the Linac Coherent Light Source (LCLS), at SLAC National …

Macromolecular crystallography at synchrotron sources has proven to be the most influential
method within structural biology, producing thousands of structures since its inception. While …

The Coherent X-ray Imaging (CXI) instrument specializes in hard X-ray, in-vacuum, high
power density experiments in all areas of science. Two main sample chambers, one …

X-ray free-electron lasers (XFELs) provide very intense X-ray pulses suitable for
macromolecular crystallography. Each X-ray pulse typically lasts for tens of femtoseconds …

We describe a concentric-flow electrokinetic injector for efficiently delivering microcrystals for
serial femtosecond X-ray crystallography analysis that enables studies of challenging …

It has long been known that toxins produced by Bacillus thuringiensis (Bt) are stored in the
bacterial cells in crystalline form. Here we describe the structure determination of the Cry3A …

An experimental system for serial femtosecond crystallography using an X-ray free-electron
laser (XFEL) has been developed. It basically consists of a sample chamber, fluid injectors …

The advent of the X-ray free electron laser (XFEL) in the last decade created the discipline of
serial crystallography but also the challenge of how crystal samples are delivered to X-ray …

Microfluidic strategies to enable the growth and subsequent serial crystallographic analysis
of micro-crystals have the potential to facilitate both structural characterization and dynamic …

The bacterial 30S ribosomal subunit is a primary antibiotic target. Despite decades of
discovery, the mechanisms by which antibiotic binding induces ribosomal dysfunction are …