Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

The crosstalk between ferroptosis and anti‐tumor immunity in the tumor microenvironment: molecular mechanisms and therapeutic controversy

Y Zheng, L Sun, J Guo, J Ma - Cancer Communications, 2023 - Wiley Online Library
The advent of immunotherapy has significantly reshaped the landscape of cancer treatment,
greatly enhancing therapeutic outcomes for multiple types of cancer. However, only a small …

Ferroptosis as a promising therapeutic strategy for melanoma

N Ta, X Jiang, Y Zhang, H Wang - Frontiers in pharmacology, 2023 - frontiersin.org
Malignant melanoma (MM) is the most common and deadliest type of skin cancer and is
associated with high mortality rates across all races and ethnicities. Although present …

[HTML][HTML] Recent advances of ferroptosis in tumor: From biological function to clinical application

S Hu, Y Chu, X Zhou, X Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis is a recently recognized form of cell death with distinct features in terms of
morphology, biochemistry, and molecular mechanisms. Unlike other types of cell death …

Erythrocyte membrane-camouflaged DNA-functionalized upconversion nanoparticles for tumor-targeted chemotherapy and immunotherapy

Q Kou, Y Huang, Y Su, L Lu, X Li, H Jiang, R Huang… - Nanoscale, 2023 - pubs.rsc.org
A synergistic combination of treatment with immunogenic cell death (ICD) inducers and
immunoadjuvants may be a practical way to boost the anticancer response and successfully …

Ferroptosis crosstalk in anti-tumor immunotherapy: molecular mechanisms, tumor microenvironment, application prospects

Y Lu, X Xie, L Luo - Apoptosis, 2024 - Springer
Immunotherapies for cancer, specifically immune checkpoint inhibition (ICI), have shown
potential in reactivating the body's immune response against tumors. However, there are …

Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment

J Wang, J Ma, Z Tai, L Li, T Zhang… - International Journal …, 2023 - Taylor & Francis
Melanoma, a highly aggressive skin tumor, exhibits notable features including
heterogeneity, a high mutational load, and innate immune escape. Despite advancements in …

Melanoma biology and treatment: a review of novel regulated cell death-based approaches

M Hsieh, SK Hsu, TY Liu, CY Wu, CC Chiu - Cancer Cell International, 2024 - Springer
The incidence of melanoma, the most lethal form of skin cancer, has increased due to
ultraviolet exposure. The treatment of advanced melanoma, particularly metastatic cases …

Harnessing the potential of non-apoptotic cell death processes in the treatment of drug-resistant melanoma

L Dong, CPD Vargas, X Tian, X Chu, C Yin… - International journal of …, 2023 - mdpi.com
Melanoma is a highly malignant skin cancer that is known for its resistance to treatments. In
recent years, there has been significant progress in the study of non-apoptotic cell death …

Two-pronged anti-cancer nanovaccines enpowered by exogenous/endogenous tumor-associated antigens

M Yin, Z Liu, Y Zhou, W Li, J Yan, D Cao… - Journal of Controlled …, 2024 - Elsevier
Cancer vaccines based on single-source (exogenous or endogenous) tumor-associated
antigens (TAAs) are often challenged by the insufficient T cell response and the …