Individual sensory neurons can be tuned to many stimuli, each driving unique, stimulus-
relevant behaviors, and the ability of multimodal nociceptor neurons to discriminate between …

Neurons that participate in sensory processing often display “ON” responses, ie, fire
transiently at the onset of a stimulus. ON transients are widespread, perhaps universal to …

Calcium (Ca2+) plays a pivotal role in modulating neuronal-mediated responses to modality-
specific sensory stimuli. Recent studies in Drosophila reveal class III (CIII) multidendritic …

Temperature sensation involves thermosensitive TRP (thermoTRP) and non-TRP channels.
Drosophila larval Class III (CIII) neurons serve as the primary cold nociceptors and express …

Investigation of the mechanism of neuronal communication underlies the fundamental
discoveries that promote health. The studies of oxytocin signaling in neurons from or within …

The capability to create an internal representation of the external world is a fundamental
aspect that unites all living higher-order organisms and ensures their survival. In this …

Temperature affects all biological processes, from the rate of cellular growth and metabolism
to the stability of proteins that make up the machinery of life itself. Thus, all organisms must …