Burkitt lymphoma (BL) is an aggressive form of B cell lymphoma that can affect children and
adults. The study of BL led to the identification of the first recurrent chromosomal aberration …

Each year~ 429,000 children and adolescents aged 0 to 19 years are expected to develop
cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high …

Background Rituximab added to chemotherapy prolongs survival among adults with B-cell
cancer. Data on its efficacy and safety in children with high-grade, mature B-cell non …

Purpose Interim positron emission tomography (PET) using the tracer,[18F]
fluorodeoxyglucose, may predict outcomes in patients with aggressive non-Hodgkin …

Acute lymphoblastic leukaemia, a malignant disorder of lymphoid progenitor cells, affects
both children and adults, with peak prevalence between the ages of 2 and 5 years. Steady …

Non-Hodgkin lymphoma is the fourth most common malignancy in children, has an even
higher incidence in adolescents, and is primarily represented by only a few histologic …

While survival has improved for Burkitt lymphoma patients, potential differences in outcome
between pediatric and adult patients remain unclear. In both age groups, survival remains …

Purpose Treatment and prognosis of pediatric non-Hodgkin lymphoma (NHL) have
improved dramatically in the last 30 years. However, the St Jude NHL staging classification …

Purpose Methotrexate plasma concentration is related to its clinical effects. Our aim was to
identify the genetic basis of interindividual variability in methotrexate pharmacokinetics in …

A previous study (LMB89) of the French Society of Pediatric Oncology for childhood mature
B-cell lymphoma (B-NHL) demonstrated a 92% 3-year event-free survival (EFS) for …