Actin dynamics, architecture, and mechanics in cell motility

L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Cofilin and actin dynamics: multiple modes of regulation and their impacts in neuronal development and degeneration

JR Bamburg, LS Minamide, ON Wiggan… - Cells, 2021 - mdpi.com
Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Mechanisms of actin disassembly and turnover

BL Goode, J Eskin, S Shekhar - Journal of Cell Biology, 2023 - rupress.org
Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Actin and endocytosis in budding yeast

BL Goode, JA Eskin, B Wendland - Genetics, 2015 - academic.oup.com
Endocytosis, the process whereby the plasma membrane invaginates to form vesicles, is
essential for bringing many substances into the cell and for membrane turnover. The …

Plasma membrane H+-ATPases sustain pollen tube growth and fertilization

RD Hoffmann, MT Portes, LI Olsen… - Nature …, 2020 - nature.com
Pollen tubes are highly polarized tip-growing cells that depend on cytosolic pH gradients for
signaling and growth. Autoinhibited plasma membrane proton (H+) ATPases (AHAs) have …

Internetwork competition for monomers governs actin cytoskeleton organization

C Suarez, DR Kovar - Nature reviews Molecular cell biology, 2016 - nature.com
Cells precisely control the formation of dynamic actin cytoskeleton networks to coordinate
fundamental processes, including motility, division, endocytosis and polarization. To support …

Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin

T Kotila, H Wioland, G Enkavi, K Kogan… - Nature …, 2019 - nature.com
The ability of cells to generate forces through actin filament turnover was an early adaptation
in evolution. While much is known about how actin filaments grow, mechanisms of their …

Actin mechanics and fragmentation

M Enrique, ML Gardel - Journal of Biological Chemistry, 2015 - ASBMB
Cell physiological processes require the regulation and coordination of both mechanical
and dynamical properties of the actin cytoskeleton. Here we review recent advances in …

Cytosolic concentrations of actin binding proteins and the implications for in vivo F-actin turnover

S Gonzalez Rodriguez, ACE Wirshing… - Journal of Cell …, 2023 - rupress.org
Understanding how numerous actin-binding proteins (ABPs) work in concert to control the
assembly, organization, and turnover of the actin cytoskeleton requires quantitative …

Phosphatidic acid counteracts S-RNase signaling in pollen by stabilizing the actin cytoskeleton

J Chen, P Wang, BHJ De Graaf, H Zhang, H Jiao… - The Plant …, 2018 - academic.oup.com
S-RNase is the female determinant of self-incompatibility (SI) in pear (Pyrus bretschneideri).
After translocation to the pollen tube, S-RNase degrades rRNA and induces pollen tube …