The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Actin cytoskeleton in the control of vesicle transport, cytoplasmic organization, and pollen tube tip growth

R Zhang, Y Xu, R Yi, J Shen, S Huang - Plant Physiology, 2023 - academic.oup.com
Pollen tubes extend rapidly via tip growth. This process depends on a dynamic actin
cytoskeleton, which has been implicated in controlling organelle movements, cytoplasmic …

Plasma membrane H+-ATPases sustain pollen tube growth and fertilization

RD Hoffmann, MT Portes, LI Olsen… - Nature …, 2020 - nature.com
Pollen tubes are highly polarized tip-growing cells that depend on cytosolic pH gradients for
signaling and growth. Autoinhibited plasma membrane proton (H+) ATPases (AHAs) have …

Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth

J Wang, J Shen, Y Xu, Y Jiang, X Qu, W Zhao… - Journal of Cell …, 2023 - rupress.org
The actin cytoskeleton is one of the targets of the pH gradient in tip-growing cells, but how
cytosolic pH regulates the actin cytoskeleton remains largely unknown. We here …

Exploring the role of the plant actin cytoskeleton: from signaling to cellular functions

G Yuan, H Gao, T Yang - International Journal of Molecular Sciences, 2023 - mdpi.com
The plant actin cytoskeleton is characterized by the basic properties of dynamic array, which
plays a central role in numerous conserved processes that are required for diverse cellular …

Mechanics of pollen tube elongation: a perspective

PB Adhikari, X Liu, RD Kasahara - Frontiers in Plant Science, 2020 - frontiersin.org
Pollen tube (PT) serves as a vehicle that delivers male gametes (sperm cells) to a female
gametophyte during double fertilization, which eventually leads to the seed formation. It is …

Activation of actin-depolymerizing factor by CDPK16-mediated phosphorylation promotes actin turnover in Arabidopsis pollen tubes

Q Wang, Y Xu, S Zhao, Y Jiang, R Yi, Y Guo… - PLoS Biology, 2023 - journals.plos.org
As the stimulus-responsive mediator of actin dynamics, actin-depolymerizing factor
(ADF)/cofilin is subject to tight regulation. It is well known that kinase-mediated …

Control of the actin cytoskeleton within apical and subapical regions of pollen tubes

Y Xu, S Huang - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
In flowering plants, sexual reproduction involves a double fertilization event, which is
facilitated by the delivery of two non-motile sperm cells to the ovule by the pollen tube …

Abiotic Stress-Induced Actin-Depolymerizing Factor 3 From Deschampsia antarctica Enhanced Cold Tolerance When Constitutively Expressed in Rice

MY Byun, LH Cui, A Lee, HG Oh, YH Yoo, J Lee… - Frontiers in …, 2021 - frontiersin.org
The Antarctic flowering plant Deschampsia antarctica is highly sensitive to climate change
and has shown rapid population increases during regional warming of the Antarctic …

Functional non‐equivalence of pollen ADF isovariants in Arabidopsis

Y Jiang, Q Lu, S Huang - The Plant Journal, 2022 - Wiley Online Library
SUMMARY ADF/cofilin is a central regulator of actin dynamics. We previously demonstrated
that two closely related Arabidopsis class IIa ADF isovariants, ADF7 and ADF10, are …