MPCLCDA: predicting circRNA–disease associations by using automatically selected meta-path and contrastive learning

W Liu, T Tang, X Lu, X Fu, Y Yang… - Briefings in …, 2023 - academic.oup.com
Circular RNA (circRNA) is closely associated with human diseases. Accordingly, identifying
the associations between human diseases and circRNA can help in disease prevention …

GCFMCL: predicting miRNA-drug sensitivity using graph collaborative filtering and multi-view contrastive learning

J Wei, L Zhuo, Z Zhou, X Lian, X Fu… - Briefings in …, 2023 - academic.oup.com
Studies have shown that the mechanism of action of many drugs is related to miRNA. In-
depth research on the relationship between miRNA and drugs can provide theoretical …

NSRGRN: a network structure refinement method for gene regulatory network inference

W Liu, Y Yang, X Lu, X Fu, R Sun… - Briefings in …, 2023 - academic.oup.com
The elucidation of gene regulatory networks (GRNs) is one of the central challenges of
systems biology, which is crucial for understanding pathogenesis and curing diseases …

Dynamic network link prediction with node representation learning from graph convolutional networks

P Mei, YH Zhao - Scientific Reports, 2024 - nature.com
Dynamic network link prediction is extensively applicable in various scenarios, and it has
progressively emerged as a focal point in data mining research. The comprehensive and …

Headtailtransfer: an efficient sampling method to improve the performance of graph neural network method in predicting sparse ncrna–protein interactions

J Wei, L Zhuo, S Pan, X Lian, X Yao, X Fu - Computers in Biology and …, 2023 - Elsevier
Noncoding RNA (ncRNA) is a functional RNA derived from DNA transcription, and most
transcribed genes are transcribed into ncRNA. ncRNA is not directly involved in the …

Identification of key candidate genes for IgA nephropathy using machine learning and statistics based bioinformatics models

M Al Mehedi Hasan, M Maniruzzaman, J Shin - Scientific Reports, 2022 - nature.com
Abstract Immunoglobulin-A-nephropathy (IgAN) is a kidney disease caused by the
accumulation of IgAN deposits in the kidneys, which causes inflammation and damage to …

An efficient model for predicting human diseases through miRNA based on multiple-types of contrastive learning

Q Liao, X Fu, L Zhuo, H Chen - Frontiers in Microbiology, 2023 - frontiersin.org
Multiple studies have demonstrated that microRNA (miRNA) can be deeply involved in the
regulatory mechanism of human microbiota, thereby inducing disease. Developing effective …

Prediction of miRNA-disease associations in microbes based on graph convolutional networks and autoencoders

Q Liao, Y Ye, Z Li, H Chen, L Zhuo - Frontiers in Microbiology, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short RNA molecular fragments that regulate gene expression by
targeting and inhibiting the expression of specific RNAs. Due to the fact that microRNAs …

Identification and validation of prognostic signature genes of bladder cancer by integrating methylation and transcriptomic analysis

D Chatterjee, SI Mou, T Sultana, MI Hosen… - Scientific Reports, 2024 - nature.com
Being a frequent malignant tumor of the genitourinary system, Bladder Urothelial Carcinoma
(BLCA) has a poor prognosis. This study focused on identifying and validating prognostic …

A method to improve the prediction performance of cancer-gene association by screening negative training samples through gene network data

M Xu, NA Abdullah, AQM Sabri - Computational Biology and Chemistry, 2024 - Elsevier
This work focuses on data sampling in cancer-gene association prediction. Currently,
researchers are using machine learning methods to predict genes that are more likely to …