[HTML][HTML] Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases
Central nervous system (CNS) innate immunity plays essential roles in infections,
neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are …
neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are …
The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction
EC Kugler, J Greenwood… - Frontiers in Cell and …, 2021 - frontiersin.org
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
The circadian regulation of food intake
E Challet - Nature Reviews Endocrinology, 2019 - nature.com
Feeding, which is essential for all animals, is regulated by homeostatic mechanisms. In
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …
Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow
Astrocytes provide neurons with essential metabolic and structural support, modulate
neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to …
neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to …
[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations
EA Turovsky, VV Golovicheva… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in
neuroprotective therapy. The protective properties of MSC were considered to be associated …
neuroprotective therapy. The protective properties of MSC were considered to be associated …
Foundations and implications of astrocyte heterogeneity during brain development and disease
AL Schober, LE Wicki-Stordeur, KK Murai… - Trends in …, 2022 - cell.com
Astrocytes play crucial roles in regulating brain circuit formation and physiology. Recent
technological advances have revealed unprecedented levels of astrocyte diversity …
technological advances have revealed unprecedented levels of astrocyte diversity …
Insulin regulates neurovascular coupling through astrocytes
AM Fernandez, L Martinez-Rachadell… - Proceedings of the …, 2022 - National Acad Sciences
Mice with insulin receptor (IR)–deficient astrocytes (GFAP-IR knockout [KO] mice) show
blunted responses to insulin and reduced brain glucose uptake, whereas IR-deficient …
blunted responses to insulin and reduced brain glucose uptake, whereas IR-deficient …
The role of glia in the physiology and pharmacology of glucagon‐like peptide‐1: implications for obesity, diabetes, neurodegeneration and glaucoma
The medical applications of glucagon‐like peptide‐1 receptor (GLP‐1R) agonists is
evergrowing in scope, highlighting the urgent need for a comprehensive understanding of …
evergrowing in scope, highlighting the urgent need for a comprehensive understanding of …
GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats
SM Fortin, RK Lipsky, R Lhamo, J Chen… - Science translational …, 2020 - science.org
The glucagon-like peptide-1 receptor (GLP-1R) agonist liraglutide is approved for the
treatment of obesity; however, there is still much to be learned regarding the neuronal sites …
treatment of obesity; however, there is still much to be learned regarding the neuronal sites …
The astrocytic Na+‐HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity
K Li, EC Gonye, RL Stornetta, CB Bayliss… - The Journal of …, 2023 - Wiley Online Library
The interoceptive homeostatic mechanism that controls breathing, blood gases and acid‐
base balance in response to changes in CO2/H+ is exquisitely sensitive, with convergent …
base balance in response to changes in CO2/H+ is exquisitely sensitive, with convergent …