Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …

Recent reports have demonstrated that oncogene amplification on extrachromosomal DNA
(ecDNA) is a frequent event in cancer, providing new momentum to explore a phenomenon …

Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …

Large amounts of antibiotics used for human therapy, as well as for farm animals and even
for fish in aquaculture, resulted in the selection of pathogenic bacteria resistant to multiple …

Mutation and horizontal gene transfer (HGT) continually give rise to new bacterial
genotypes. Infrequently, such new bacterial genotypes establish and spread in the larger …

Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

Why do bacteria have shape? Is morphology valuable or just a trivial secondary
characteristic? Why should bacteria have one shape instead of another? Three broad …

We have developed a general profile for the proteins of the TetR family of repressors. The
stretch that best defines the profile of this family is made up of 47 amino acid residues that …