Effective Action of Silymarin against Ketamine-induced Schizophrenia in Male Mice: Insight into the Biochemical and Molecular Mechanisms of Action

B Ben-Azu, AR Fokoua, OS Annafi, OG Adebayo… - Journal of Psychiatric …, 2024 - Elsevier
Background Neurochemical dysregulations resulting from N-methyl-D-aspartate
hypofunction (NMDA), are exacerbated by neuroimmune and oxidative stress and are …

[HTML][HTML] Adverse hematological profiles associated with chlorpromazine antipsychotic treatment in male rats: Preventive and reversal mechanisms of taurine and …

OM Obukohwo, B Ben-Azu, EK Nwangwa, EP Ohwin… - Toxicology Reports, 2024 - Elsevier
Chlorpromazine (CPZ) is one of the most effective antipsychotic drugs used for managing
psychotic related disorders owing to its dopamine receptor blocking action. However …

Effects of combined postweaning social isolation and ketamine administration on schizophrenia-like behaviour in male Sprague Dawley rats

KB Shangase, M Luvuno, M Mabandla - Behavioural Brain Research, 2024 - Elsevier
The pathophysiology behind negative and cognitive symptoms of schizophrenia is not well
understood, thus limiting the effectiveness of treatment on these symptoms. Developing …

Co-exposure to Aluminium and Cadmium Mediates Postpartum Maternal Variation in Brain Architecture and Behaviour of Mice; Involvement of Oxido-nitrergic and …

PC Ichipi-Ifukor, SO Asagba, FI Achuba - Biological Trace Element …, 2024 - Springer
Most research has not been done on the possible relationship between pregnant women's
cross-metal exposures and postpartum neuroendocrine functions. The purpose of this study …

[HTML][HTML] Diosgenin reverses posttraumatic stress disorder in mice by augmenting neurochemical release and inhibiting HPA axis dysfunction, oxidative stress, and …

B Ben-Azu, OG Adebayo, A Adebesin… - Journal of Affective …, 2024 - Elsevier
Post-traumatic stress disorder (PTSD) is a mental disorder linked to neurochemical,
hypothalamic-pituitary-adrenal (HPA)-axis dysregulations, inflammatory and pro-oxidant …

[HTML][HTML] Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced …

B Ben-Azu, OG Adebayo, AR Fokoua, JE Onuelu… - Brain Disorders, 2024 - Elsevier
Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation
can provide normalization of neurochemical homeostasis and neurotrophic support in the …

[HTML][HTML] Adaptogenic action of diosgenin againsts chronic unpredictable mild stress-induced neuroimmune dysfunction of HPA axis reverses psychiatric behavior in …

B Ben-Azu, EO Chidebe, PEY Toloyai… - … Traditional Medicine and …, 2024 - Elsevier
Background Stressful life experiences are associated with neurobehavioral abnormalities,
such as anxiogenic-related depression and cognitive decline. Reportedly, adaptogens are …

[PDF][PDF] Brain Disorders

B Ben-Azu, OG Adebayo, AR Fokoua, JE Onuelu… - dspace.library.uvic.ca
Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation
can provide normalization of neurochemical homeostasis and neurotrophic support in the …

[HTML][HTML] Risperidona: qué es y para qué se usa

D Aparicio - psyciencia.com
La risperidona es un medicamento antipsicótico de segunda generación que se ha
convertido en un pilar importante en el tratamiento de trastornos mentales graves. Aprobada …