Environmental risk factors have been implicated in adverse health effects. Previous
epidemiological studies on environmental risk factors mainly analyzed the impact of single …

Manganese (Mn) is an essential element that is involved in the synthesis and activation of
many enzymes and in the regulation of the metabolism of glucose and lipids in humans. In …

Background The association of trimethylamine-N-oxide (TMAO), a microbiota-dependent
metabolite from dietary choline and carnitine, with type 2 diabetes was inconsistent …

Background Epidemiologic studies suggest toxic metals are linked with diabetes and
cardiovascular disease, while experimental studies indicate nutritionally essential metals …

Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

Purpose We aimed to examine the prospective association between manganese, iron,
copper, zinc, iodine, selenium, selenoprotein P, free zinc, and their interplay, with incident …

Micronutrients influence hormone action and host metabolism. Dietary minerals, trace
elements, and vitamins can alter blood glucose and cellular glucose metabolism, and …

Purpose We aimed to evaluate age-dependent changes of six trace elements
(TE)[manganese (Mn), iron (Fe), zinc (Zn), copper (Cu), iodine (I), and selenium (Se)] over a …

The long-term associations between multiple metals and incident diabetes are uncertain.
We aimed to examine the relationship between plasma concentrations of 23 metals and the …

Abstract Background Congenital heart defects (CHDs) are the most common congenital
malformations with a complex etiology, and environmental factors play an important role …