Recent studies found that unbalanced copper homeostasis affect tumor growth, causing
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …

Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …

Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …

Nanomedicines, while having been approved for cancer therapy, present many challenges
such as low stability, rapid clearance, and nonspecificity leading to off-target toxicity …

Background Recent advances in nanotechnology have offered new hope for cancer
detection, prevention, and treatment. Nanomedicine, a term for the application of …

Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …

New complexes of zinc (II) and copper (II) with 2-furoic acid (Hfur), acetic acids and N-donor
ligands with the compositions [Zn2 (fur) 4] n (1),[Zn2 (fur) 4 (NH2py) 2](2, NH2py= 3 …

Copper is an endogenous metal ion that has been studied to prepare a new antitumoral
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …

The significantly increased copper level in tumor tissues and serum indicates the close
association of copper ions with tumor development, making copper ions attractive targets in …

Abstract Density Functional Theoretical (DFT) and molecular docking studies have been
used to elucidate the antineoplastic potential of the ligand 6-Methylpyridine-2-carbaldehyde …