Background: Patients presenting with critical limb-threatening ischemia (CLTI) have been
increasing in number over the years. They represent a high-risk population, especially in …

Diabetes mellitus is a highly prevalent disease globally and contributes to significant
morbidity and mortality. As a consequence of multiple pathophysiologic changes which are …

Diabetes-related foot disease (DFD) is a widely feared complication among people who live
with diabetes. In Australia and globally, rates of disability, cardio-vascular disease, lower …

Background Diabetes-related limb ischemia is a challenge for lower extremity amputation.
Aurora Kinase A (AURKA) is an essential serine/threonine kinase for mitosis, while its role in …

Purpose Chronic limb-threatening ischemia in patients with diabetes is associated with a
high risk of adverse outcomes. The associated co-morbidities, the heterogeneity of foot …

Background and Objectives: Atherosclerosis is a multifactorial process in which
inflammatory markers have both therapeutic and prognostic roles. Recent studies bring into …

Guidelines point to the ankle-brachial index (ABI) as a non-invasive tool for the initial
diagnosis of lower extremity artery disease (LEAD). Questions have been raised whether …

Review: A common chronic health problem among Saudi Arabians is diabetes mellitus
(DM). One of the most serious complications of diabetes is diabetic foot (DMF). Aim: The …

Critical limb ischemia (CLI) is a severe form of peripheral artery diseases (PAD) and
seriously endangers the health of people. Therapeutic angiogenesis represents an …

Aims This study assessed whether changes associated with cerebral small vessel disease
(CSVD) evaluated from head computed tomography (CT) images captured for non-related …