Mesenchymal stem cells (MSCs) hold great potential as a regenerative therapy for stroke,
leading to increased repair and functional recovery in animal models of cerebral ischaemia …

Stroke, a global disease with a high disability rate, has limited options for functional
rehabilitation and results in an adverse impact on patients' lives. In recent years …

Ischemic stroke (IS) is a serious cerebrovascular disease with high morbidity and disability
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …

Although intravenous administration of mesenchymal stem cells (MSCs) is effective for
experimental stroke, low engraftment and the limited functional capacity of transplanted cells …

Glycosaminoglycans (GAGs), including heparan sulfates and chondroitin sulfates, are major
components of the extracellular matrix. Upon interacting with heparin binding growth factors …

Background The transient middle cerebral artery occlusion (tMCAO) model is used for
studying the molecular mechanisms of ischemic damage and neuroprotection. Numerous …

Stem cells have been used for regenerative and therapeutic purposes in a variety of
diseases. In ischemic brain injury, preclinical studies have been promising, but have failed …

Neurological disorders are recognized as major causes of death and disability worldwide.
Because of this, they represent one of the largest public health challenges. With awareness …

Transplantation of human bone marrow mesenchymal stem cells (hMSCs) stands as a
potent stroke therapy, but its exact mechanism remains unknown. This study investigated the …

Abstract Background Mesenchymal stem cells (MSCs) hold great potential as a therapy for
stroke and have previously been shown to promote recovery in preclinical models of …