Molecular mechanisms of the efficacy of cold atmospheric pressure plasma (CAP) in cancer treatment

ML Semmler, S Bekeschus, M Schäfer, T Bernhardt… - Cancers, 2020 - mdpi.com
Recently, the potential use of cold atmospheric pressure plasma (CAP) in cancer treatment
has gained increasing interest. Especially the enhanced selective killing of tumor cells …

Current state of cold atmospheric plasma and cancer‐immunity cycle: therapeutic relevance and overcoming clinical limitations using hydrogels

M Živanić, A Espona‐Noguera, A Lin… - Advanced …, 2023 - Wiley Online Library
Cold atmospheric plasma (CAP) is a partially ionized gas that gains attention as a well‐
tolerated cancer treatment that can enhance anti‐tumor immune responses, which are …

Clinical experience with cold plasma in the treatment of locally advanced head and neck cancer

HR Metelmann, C Seebauer, V Miller, A Fridman… - Clinical Plasma …, 2018 - Elsevier
Purpose Cold atmospheric pressure plasma (CAP) is well known for inactivating microbial
pathogens and stimulation of tissue regeneration in chronic wounds. Several authors have …

Low-temperature plasma for biology, hygiene, and medicine: Perspective and roadmap

M Laroussi, S Bekeschus, M Keidar… - … on Radiation and …, 2021 - ieeexplore.ieee.org
Plasma, the fourth and most pervasive state of matter in the visible universe, is a fascinating
medium that is connected to the beginning of our universe itself. Man-made plasmas are at …

Cold atmospheric plasma and plasma-activated medium trigger RONS-based tumor cell apoptosis

G Bauer, D Sersenová, DB Graves, Z Machala - Scientific reports, 2019 - nature.com
The selective in vitro anti-tumor mechanisms of cold atmospheric plasma (CAP) and plasma-
activated media (PAM) follow a sequential multi-step process. The first step involves the …

Plasma-activated medium triggers cell death and the presentation of immune activating danger signals in melanoma and pancreatic cancer cells

A Azzariti, RM Iacobazzi, R Di Fonte, L Porcelli… - Scientific reports, 2019 - nature.com
Over the past decade, cold atmospheric plasmas have shown promising application in
cancer therapy. The therapeutic use of plasma-activated media is a topic addressed in an …

Nanosecond-pulsed DBD plasma-generated reactive oxygen species trigger immunogenic cell death in A549 lung carcinoma cells through intracellular oxidative …

A Lin, B Truong, S Patel, N Kaushik, EH Choi… - International journal of …, 2017 - mdpi.com
A novel application for non-thermal plasma is the induction of immunogenic cancer cell
death for cancer immunotherapy. Cells undergoing immunogenic death emit danger signals …

[HTML][HTML] The synergistic effect between hydrogen peroxide and nitrite, two long-lived molecular species from cold atmospheric plasma, triggers tumor cells to induce …

G Bauer - Redox biology, 2019 - Elsevier
Nitrite and H 2 O 2 are long-lived species in cold atmospheric plasma and plasma-activated
medium. It is known that their synergistic interaction is required for selective apoptosis …

Non-thermal plasma induces immunogenic cell death in vivo in murine CT26 colorectal tumors

AG Lin, B Xiang, DJ Merlino, TR Baybutt, J Sahu… - …, 2018 - Taylor & Francis
Immunogenic cell death is characterized by the emission of danger signals that facilitate
activation of an adaptive immune response against dead-cell antigens. In the case of cancer …

The emerging role of gas plasma in oncotherapy

X Dai, K Bazaka, DJ Richard, ERW Thompson… - Trends in …, 2018 - cell.com
Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that
can supplement the existing set of treatment modalities and, when combined with other …