Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …

Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Preeclampsia is defined as new-onset hypertension after the 20th wk of gestation along with
evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the …

Background: Effective screening for term preeclampsia is provided by a combination of
maternal factors with measurements of mean arterial pressure, serum placental growth …

Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

Preeclampsia is a serious complication of pregnancy where it affects 5–8% of all
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …

Preeclampsia is a clinical syndrome defined as the new onset of hypertension and
proteinuria during the second half of pregnancy. 1 It afflicts 3% to 5% of pregnancies and is …