Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive
poultry disease caused by IBD virus (IBDV). The consequent immunosuppression increases …

Innate immunity is not only the first line of host defense against pathogenic infection, but also
the cornerstone of adaptive immune response. Upon pathogenic infection, pattern …

Early biochemical studies of viral replication suggested that most viruses produce double-
stranded RNA (dsRNA), which is essential for the induction of the host immune response …

Infectious bursal disease virus (IBDV), a double-stranded RNA virus, causes
immunosuppression and high mortality in 3–6-week-old chickens. Innate immune defense is …

Infectious bursal disease virus (IBDV) affects immature B lymphocytes of the bursa of
Fabricius and may cause significant immunosuppression. It continues to be a leading cause …

Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious
disease, resulting in considerable economic losses in the world poultry industry. Although …

The ability to sense and respond to infection is essential for life. Viral infection produces
double-stranded RNAs (dsRNAs) that are sensed by proteins that recognize the structure of …

Subclinical immunosuppression in chickens is an important but often underestimated factor
in the subsequent development of clinical disease. Immunosuppression can be caused by …

Ubiquitination is an important reversible post-translational modification. Many viruses hijack
the host ubiquitin system to enhance self-replication. In the present study, we found that …

Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive avian
disease caused by infectious bursal disease virus (IBDV). In recent years, remarkable …