Cholesterol, lipid rafts, and disease

K Simons, R Ehehalt - The Journal of clinical investigation, 2002 - Am Soc Clin Investig
Nonstandard abbreviations used: glycophosphatidylinositolanchored (GPI-anchored);
endothelial nitric oxide synthase (eNOS); β-secretase (BACE); endoplasmic reticulum (ER); …

Acute human immunodeficiency virus type 1 infection

JO Kahn, BD Walker - New England Journal of Medicine, 1998 - Mass Medical Soc
Acute human immunodeficiency virus type 1 (HIV-1) infection is a transient symptomatic
illness associated with high-titer HIV-1 replication and a robust and expansive immunologic …

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

A Rosa, A Chande, S Ziglio, V De Sanctis, R Bertorelli… - Nature, 2015 - nature.com
HIV-1 Nef, a protein important for the development of AIDS, has well-characterized effects on
host membrane trafficking and receptor downregulation. By an unidentified mechanism, Nef …

Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers

X Lian, C Gao, X Sun, C Jiang, KB Einkauf… - Science translational …, 2021 - science.org
Increasing evidence suggests that durable drug-free control of HIV-1 replication is enabled
by effective cellular immune responses that may induce an attenuated viral reservoir …

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

R Zufferey, D Nagy, RJ Mandel, L Naldini… - Nature …, 1997 - nature.com
Retroviral vectors derived from lentiviruses such as HIV-1 are promising tools for human
gene therapy because they mediate the in vivo delivery and long-term expression of …

HLA B* 5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

SA Migueles, MS Sabbaghian… - Proceedings of the …, 2000 - National Acad Sciences
A unique cohort of HIV-1-infected long term nonprogressors (LTNP) with normal CD4+ T cell
counts and< 50 copies/ml of plasma were prospectively recruited for study. HLA typing …

Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy

SG Deeks, BD Walker - Immunity, 2007 - cell.com
Chronic viral infections can appear in two very different forms: those that are typically
immunologically contained after acute symptomatic infection, such as Epstein-Barr virus …

Structural biology of HIV

BG Turner, MF Summers - Journal of molecular biology, 1999 - Elsevier
The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …

The Trojan exosome hypothesis

SJ Gould, AM Booth… - Proceedings of the …, 2003 - National Acad Sciences
We propose that retroviruses exploit a cell-encoded pathway of intercellular vesicle traffic,
exosome exchange, for both the biogenesis of retroviral particles and a low-efficiency but …

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

NJ Deacon, A Tsykin, A Solomon, K Smith… - Science, 1995 - science.org
A blood donor infected with human immunodeficiency virus-type 1 (HIV-1) and a cohort of
six blood or blood product recipients infected from this donor remain free of HIV-1-related …