Key determinants for the development of an allergic response to an otherwise 'harmless'
food protein involve different factors like the predisposition of the individual, the timing, the …

Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Glycosylation is one of the most common post-translational modifications (PTMs) of proteins.
At least 50% of human proteins are glycosylated with some estimates being as high as 70 …

In comparison with genomics and proteomics, the advancement of glycomics has faced
unique challenges in the pursuit of developing analytical and biochemical tools and …

Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

A multitude of monoclonal IgG antibodies directed against a variety of therapeutic targets is
currently being developed and produced by biotechnological companies. The biological …

The O‐glycosylation of Ser and Thr by N‐acetylgalactosamine‐linked (mucin‐type)
oligosaccharides is often overlooked in protein analysis. Three characteristics make O …

Glycoproteins are known to exhibit multiple biological functions. In order to assign distinct
functional properties to defined structural features, detailed information on the respective …