Staufen‐mediated mRNA decay

E Park, LE Maquat - Wiley interdisciplinary reviews: RNA, 2013 - Wiley Online Library
Staufen1 (STAU1)‐mediated mRNA decay (SMD) is an mRNA degradation process in
mammalian cells that is mediated by the binding of STAU1 to a STAU1‐binding site (SBS) …

The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity

JE Heraud-Farlow, MA Kiebler - Trends in neurosciences, 2014 - cell.com
Staufen (Stau) proteins belong to a family of RNA-binding proteins (RBPs) that are important
for RNA localisation in many organisms. In this review we discuss recent findings on the …

Mammalian Staufen 1 is recruited to stress granules and impairs their assembly

MG Thomas, LJM Tosar, MA Desbats… - Journal of cell …, 2009 - journals.biologists.com
Stress granules are cytoplasmic mRNA-silencing foci that form transiently during the stress
response. Stress granules harbor abortive translation initiation complexes and are in …

Coordination of endoplasmic reticulum and mRNA localization to the yeast bud

M Schmid, A Jaedicke, TG Du, RP Jansen - Current biology, 2006 - cell.com
Localization of messenger RNAs and local protein synthesis contribute to asymmetric
protein distribution not only of cytoplasmic but also of membrane or secreted proteins [1, 2] …

L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes

CR Neil, SP Jeschonek, SE Cabral… - Molecular biology of …, 2021 - Am Soc Cell Biol
Ribonucleoprotein (RNP) granules are membraneless compartments within cells, formed by
phase separation, that function as regulatory hubs for diverse biological processes …

The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

B Goetze, F Tuebing, Y Xie, MM Dorostkar… - The Journal of cell …, 2006 - rupress.org
Mammalian Staufen2 (Stau2) is a member of the double-stranded RNA-binding protein
family. Its expression is largely restricted to the brain. It is thought to play a role in the …

Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity

E Park, ML Gleghorn… - Proceedings of the …, 2013 - National Acad Sciences
Staufen (STAU) 1-mediated mRNA decay (SMD) is a posttranscriptional regulatory
mechanism in mammals that degrades mRNAs harboring a STAU1-binding site (SBS) in …

Control of messenger RNA fate by RNA‐binding proteins: an emphasis on mammalian spermatogenesis

RK Idler, W Yan - Journal of andrology, 2012 - Wiley Online Library
Posttranscriptional status of messenger RNAs (mRNA) can be affected by many factors,
most of which are RNA‐binding proteins (RBP) that either bind mRNA in a nonspecific …

Pathways for mRNA localization in the cytoplasm

K Czaplinski, RH Singer - Trends in biochemical sciences, 2006 - cell.com
Studies of the intracellular localization of mRNA have clearly demonstrated that certain
subsets of mRNA are concentrated in discrete locations within the cytoplasm. Localization is …

Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-β-related mRNA during oogenesis

K Czaplinski, T Köcher, M Schelder, A Segref, M Wilm… - Developmental cell, 2005 - cell.com
Asymmetric distribution of cellular components underlies many biological processes, and
the localization of mRNAs within domains of the cytoplasm is one important mechanism of …