Introduction: Adenocarcinoma is the most common histologic type of lung cancer. To
address advances in oncology, molecular biology, pathology, radiology, and surgery of lung …

Aims Activating mutations in the gene encoding epidermal growth factor receptor (EGFR)
can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib in patients with …

The new International Association for the Study of Lung Cancer/American Thoracic
Society/European Respiratory Society lung adenocarcinoma classification provides, for the …

The targeted treatment of advanced non-small-cell lung cancer (NSCLC) depends on
confirmation of activating somatic EGFR mutation. The aim of the study was to evaluate the …

Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and
non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the …

Background: The prognosis of metastatic non-small cell lung cancer (NSCLC) is still poor.
Activating epithelial growth factor receptor (EGFR) mutations are important genetic …

Background The aim of this study was to evaluate the effect of coaxial guide needle gauge
(18 vs. 19 gauge) on the risk of pneumothorax and chest tube placement after CT-guided …

Lack of new anti-cancer and anti-infective agents directed the pharmaceutical research to
natural products' discovery especially from actinomycetes as one of the major sources of …

BACKGROUND Personalized oncology requires molecular analysis of tumor cells. Several
studies have demonstrated that cytological material is suitable for DNA analysis, but to the …

With increasing requests for the evaluation of prognostic and predictive molecular
biomarkers, great attention must be paid to the preanalytical issues regarding sample quality …